4NOK

Crystal structure of proenzyme asparaginyl endopeptidase (AEP)/Legumain at pH 7.5

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004197	molecular_function	cysteine-type endopeptidase activity
A	0006508	biological_process	proteolysis
A	0008233	molecular_function	peptidase activity
A	0051603	biological_process	proteolysis involved in protein catabolic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: ACT_SITE => ECO:0000269|PubMed:9891971

Chain	Residue	Details
A	HIS150

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site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: Nucleophile => ECO:0000269|PubMed:9891971

Chain	Residue	Details
A	CYS191

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site_id	SWS_FT_FI3
Number of Residues	1
Details	SITE: Cleavage; by autolysis

Chain	Residue	Details
A	ASN325

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site_id	SWS_FT_FI4
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASN93
A	ASN169
A	ASN265
A	ASN274

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