4LCC

Crystal structure of a human MAIT TCR in complex with a bacterial antigen bound to humanized bovine MR1

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
C	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
C	0005576	cellular_component	extracellular region
C	0005765	cellular_component	lysosomal membrane
C	0006955	biological_process	immune response
C	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
C	0023026	molecular_function	MHC class II protein complex binding
C	0031902	cellular_component	late endosome membrane
C	0042605	molecular_function	peptide antigen binding
C	0042612	cellular_component	MHC class I protein complex
C	0042613	cellular_component	MHC class II protein complex
C	0050778	biological_process	positive regulation of immune response
C	0050870	biological_process	positive regulation of T cell activation

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	BINDING SITE FOR RESIDUE 1XL C 401

Chain	Residue
A	TYR95
C	ARG207
C	ILE209
C	TYR265
C	TRP269
B	GLU99
C	TYR120
C	PHE121
C	ARG122
C	SER137
C	LYS156
C	TYR175
C	TRP182

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 C 402

Chain	Residue
A	SER27
C	ARG174
C	TRP277
C	ARG280

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site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 301

Chain	Residue
A	ARG59
A	GLN79
A	LYS81

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site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 B 301

Chain	Residue
B	GLY164
B	HIS208
B	ARG210
C	LYS296
C	ARG298

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site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 302

Chain	Residue
B	VAL167
B	HIS168
B	SER169

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YSCRVKH

Chain	Residue	Details
C	TYR77-HIS83
C	TYR367-HIS373

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498

Chain	Residue	Details
C	GLN266
B	ASN185
C	SER137
C	ARG207
C	TYR265

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site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: covalent => ECO:0000250|UniProtKB:Q95460

Chain	Residue	Details
C	LYS156

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site_id	SWS_FT_FI3
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000305

Chain	Residue	Details
C	ASN198

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