4KKD
The X-ray crystal structure of Mannose-binding lectin-associated serine proteinase-3 reveals the structural basis for enzyme inactivity associated with the 3MC syndrome
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE IMD B 801 |
| Chain | Residue |
| B | PRO439 |
| B | LEU443 |
| B | LEU460 |
| B | PHE461 |
| B | TRP678 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | ACT_SITE: Charge relay system => ECO:0000250 |
| Chain | Residue | Details |
| A | HIS497 | |
| A | ILE554 | |
| A | SER664 | |
| B | HIS497 | |
| B | ILE554 | |
| B | SER664 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by autolysis => ECO:0000269|PubMed:11290788 |
| Chain | Residue | Details |
| A | ARG449 | |
| B | ARG449 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19139490 |
| Chain | Residue | Details |
| A | ASN385 | |
| B | ASN385 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:11290788, ECO:0000269|PubMed:16335952 |
| Chain | Residue | Details |
| A | ASN407 | |
| B | ASN407 |
