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4JC0

Crystal structure of Thermotoga maritima holo RimO in complex with pentasulfide, Northeast Structural Genomics Consortium Target VR77

Functional Information from GO Data
ChainGOidnamespacecontents
A0003824molecular_functioncatalytic activity
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006400biological_processtRNA modification
A0016740molecular_functiontransferase activity
A0018339biological_processpeptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid
A0035596molecular_functionmethylthiotransferase activity
A0035599molecular_functionaspartic acid methylthiotransferase activity
A0046872molecular_functionmetal ion binding
A0051536molecular_functioniron-sulfur cluster binding
A0051539molecular_function4 iron, 4 sulfur cluster binding
A0103039molecular_functionprotein methylthiotransferase activity
B0003824molecular_functioncatalytic activity
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0006400biological_processtRNA modification
B0016740molecular_functiontransferase activity
B0018339biological_processpeptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid
B0035596molecular_functionmethylthiotransferase activity
B0035599molecular_functionaspartic acid methylthiotransferase activity
B0046872molecular_functionmetal ion binding
B0051536molecular_functioniron-sulfur cluster binding
B0051539molecular_function4 iron, 4 sulfur cluster binding
B0103039molecular_functionprotein methylthiotransferase activity
Functional Information from PDB Data
site_idAC1
Number of Residues14
DetailsBINDING SITE FOR RESIDUE FS5 A 501
ChainResidue
AGLY9
AARG150
ACYS152
ACYS155
AILE157
AGLN192
ACYS10
ALYS12
AASN13
ACYS46
AALA47
APHE48
ACYS79
ACYS148

site_idAC2
Number of Residues17
DetailsBINDING SITE FOR RESIDUE FS5 B 501
ChainResidue
BGLY9
BCYS10
BLYS12
BASN13
BCYS46
BALA47
BPHE48
BCYS79
BCYS148
BARG150
BCYS152
BPHE154
BCYS155
BILE157
BLYS161
BGLN192
BHIS229

Functional Information from PROSITE/UniProt
site_idPS01278
Number of Residues21
DetailsMTTASE_RADICAL Methylthiotransferase radical SAM domain signature. VkIsdGCdrgCTFCsIpsfkG
ChainResidueDetails
AVAL142-GLY162

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues12
DetailsBINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01865, ECO:0000269|PubMed:23542644
ChainResidueDetails
BCYS10
BCYS46
BCYS79
BCYS148
BCYS152
BCYS155
ACYS148
ACYS152
ACYS155
ACYS10
ACYS46
ACYS79

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PDB entries from 2024-05-15

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