4I0C

The structure of the camelid antibody cAbHuL5 in complex with human lysozyme

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003796	molecular_function	lysozyme activity
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0006954	biological_process	inflammatory response
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0019730	biological_process	antimicrobial humoral response
A	0031640	biological_process	killing of cells of another organism
A	0035578	cellular_component	azurophil granule lumen
A	0035580	cellular_component	specific granule lumen
A	0042742	biological_process	defense response to bacterium
A	0042802	molecular_function	identical protein binding
A	0050829	biological_process	defense response to Gram-negative bacterium
A	0050830	biological_process	defense response to Gram-positive bacterium
A	0070062	cellular_component	extracellular exosome
A	1904724	cellular_component	tertiary granule lumen
B	0003796	molecular_function	lysozyme activity
B	0005576	cellular_component	extracellular region
B	0005615	cellular_component	extracellular space
B	0006954	biological_process	inflammatory response
B	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
B	0019730	biological_process	antimicrobial humoral response
B	0031640	biological_process	killing of cells of another organism
B	0035578	cellular_component	azurophil granule lumen
B	0035580	cellular_component	specific granule lumen
B	0042742	biological_process	defense response to bacterium
B	0042802	molecular_function	identical protein binding
B	0050829	biological_process	defense response to Gram-negative bacterium
B	0050830	biological_process	defense response to Gram-positive bacterium
B	0070062	cellular_component	extracellular exosome
B	1904724	cellular_component	tertiary granule lumen

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 201

Chain	Residue
A	GLY72
B	ASN66

---

site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 202

Chain	Residue
A	ARG101
A	ARG101

---

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 203

Chain	Residue
A	ARG21
D	HOH218
D	HOH238

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 204

Chain	Residue
A	ALA108
A	HOH390
A	HOH391
A	GLN58
A	ASN60

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL B 201

Chain	Residue
B	LYS33
B	HOH370
C	SER125
C	SER126
C	HOH318

---

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL B 202

Chain	Residue
B	GLN58
B	ILE59
B	ASN60
B	TRP64
B	ALA108
B	TRP109
B	HOH358

---

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL C 201

Chain	Residue
C	LYS97
C	SER102
C	SER105

---

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL C 202

Chain	Residue
B	ARG119
B	GLN123
C	THR123

---

Functional Information from PROSITE/UniProt

site_id	PS00128
Number of Residues	19
Details	GLYCOSYL_HYDROL_F22_1 Glycosyl hydrolases family 22 (GH22) domain signature. ChlsCsaLlqdNIadavaC

Chain	Residue	Details
A	CYS77-CYS95

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE:

Chain	Residue	Details
A	GLU35
A	ASP53
B	GLU35
B	ASP53

---