4EKW

Crystal structure of the NavAb voltage-gated sodium channel (wild-type, 3.2 A)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001518	cellular_component	voltage-gated sodium channel complex
A	0005216	molecular_function	monoatomic ion channel activity
A	0005248	molecular_function	voltage-gated sodium channel activity
A	0005261	molecular_function	monoatomic cation channel activity
A	0005886	cellular_component	plasma membrane
A	0006811	biological_process	monoatomic ion transport
A	0016020	cellular_component	membrane
A	0035725	biological_process	sodium ion transmembrane transport
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding
A	0055085	biological_process	transmembrane transport
A	0086010	biological_process	membrane depolarization during action potential
B	0001518	cellular_component	voltage-gated sodium channel complex
B	0005216	molecular_function	monoatomic ion channel activity
B	0005248	molecular_function	voltage-gated sodium channel activity
B	0005261	molecular_function	monoatomic cation channel activity
B	0005886	cellular_component	plasma membrane
B	0006811	biological_process	monoatomic ion transport
B	0016020	cellular_component	membrane
B	0035725	biological_process	sodium ion transmembrane transport
B	0042802	molecular_function	identical protein binding
B	0046872	molecular_function	metal ion binding
B	0055085	biological_process	transmembrane transport
B	0086010	biological_process	membrane depolarization during action potential
C	0001518	cellular_component	voltage-gated sodium channel complex
C	0005216	molecular_function	monoatomic ion channel activity
C	0005248	molecular_function	voltage-gated sodium channel activity
C	0005261	molecular_function	monoatomic cation channel activity
C	0005886	cellular_component	plasma membrane
C	0006811	biological_process	monoatomic ion transport
C	0016020	cellular_component	membrane
C	0035725	biological_process	sodium ion transmembrane transport
C	0042802	molecular_function	identical protein binding
C	0046872	molecular_function	metal ion binding
C	0055085	biological_process	transmembrane transport
C	0086010	biological_process	membrane depolarization during action potential
D	0001518	cellular_component	voltage-gated sodium channel complex
D	0005216	molecular_function	monoatomic ion channel activity
D	0005248	molecular_function	voltage-gated sodium channel activity
D	0005261	molecular_function	monoatomic cation channel activity
D	0005886	cellular_component	plasma membrane
D	0006811	biological_process	monoatomic ion transport
D	0016020	cellular_component	membrane
D	0035725	biological_process	sodium ion transmembrane transport
D	0042802	molecular_function	identical protein binding
D	0046872	molecular_function	metal ion binding
D	0055085	biological_process	transmembrane transport
D	0086010	biological_process	membrane depolarization during action potential

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PX4 A 1301

Chain	Residue
A	GLY1164
A	GLU1165
B	TRP1195
B	ILE1199

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site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE PO4 A 1302

Chain	Residue
A	SER1034

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site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PX4 B 1301

Chain	Residue
A	TRP1195
B	GLY1164

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site_id	AC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE PX4 B 1302

Chain	Residue
A	TYR1191

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site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE PO4 B 1303

Chain	Residue
B	TYR1193

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site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PX4 C 1301

Chain	Residue
C	GLY1164
C	PHE1167
C	TYR1168
D	TRP1195

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site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PO4 C 1302

Chain	Residue
C	ILE1097
D	LEU1151

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site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PX4 D 1301

Chain	Residue
C	VAL1190
C	TYR1191
C	PRO1192

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site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PO4 D 1302

Chain	Residue
C	TRP1195
D	GLY1164

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