Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4CHG

Crystal structure of VapBC15 complex from Mycobacterium tuberculosis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0001666	biological_process	response to hypoxia
A	0004518	molecular_function	nuclease activity
A	0004540	molecular_function	RNA nuclease activity
A	0016787	molecular_function	hydrolase activity
A	0045926	biological_process	negative regulation of growth
A	0046872	molecular_function	metal ion binding
B	0000287	molecular_function	magnesium ion binding
B	0001666	biological_process	response to hypoxia
B	0004518	molecular_function	nuclease activity
B	0004540	molecular_function	RNA nuclease activity
B	0016787	molecular_function	hydrolase activity
B	0045926	biological_process	negative regulation of growth
B	0046872	molecular_function	metal ion binding
C	0000287	molecular_function	magnesium ion binding
C	0001666	biological_process	response to hypoxia
C	0004518	molecular_function	nuclease activity
C	0004540	molecular_function	RNA nuclease activity
C	0016787	molecular_function	hydrolase activity
C	0045926	biological_process	negative regulation of growth
C	0046872	molecular_function	metal ion binding
D	0000287	molecular_function	magnesium ion binding
D	0001666	biological_process	response to hypoxia
D	0004518	molecular_function	nuclease activity
D	0004540	molecular_function	RNA nuclease activity
D	0016787	molecular_function	hydrolase activity
D	0045926	biological_process	negative regulation of growth
D	0046872	molecular_function	metal ion binding
E	0000287	molecular_function	magnesium ion binding
E	0001666	biological_process	response to hypoxia
E	0004518	molecular_function	nuclease activity
E	0004540	molecular_function	RNA nuclease activity
E	0016787	molecular_function	hydrolase activity
E	0045926	biological_process	negative regulation of growth
E	0046872	molecular_function	metal ion binding
F	0000287	molecular_function	magnesium ion binding
F	0001666	biological_process	response to hypoxia
F	0004518	molecular_function	nuclease activity
F	0004540	molecular_function	RNA nuclease activity
F	0016787	molecular_function	hydrolase activity
F	0045926	biological_process	negative regulation of growth
F	0046872	molecular_function	metal ion binding
G	0001666	biological_process	response to hypoxia
G	0045927	biological_process	positive regulation of growth
G	0046872	molecular_function	metal ion binding
H	0001666	biological_process	response to hypoxia
H	0045927	biological_process	positive regulation of growth
H	0046872	molecular_function	metal ion binding
I	0001666	biological_process	response to hypoxia
I	0045927	biological_process	positive regulation of growth
I	0046872	molecular_function	metal ion binding
J	0001666	biological_process	response to hypoxia
J	0045927	biological_process	positive regulation of growth
J	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN B 1133

Chain	Residue
B	ASP96
B	ASP114
B	ASP116
H	GLU67

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN D 1133

Chain	Residue
D	ASP96
D	ASP114
D	ASP116
I	GLU67

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN F 1133

Chain	Residue
F	ASP114
F	ASP116
J	GLU67
F	ASP96

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN A 1133

Chain	Residue
A	ASP96
A	ASP114
A	ASP116
G	GLU67

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG B 1134

Chain	Residue
B	ASP96
B	HOH2003
B	HOH2004
B	HOH2022
B	HOH2023
H	GLU67

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG D 1134

Chain	Residue
D	ASP96
D	HOH2003
D	HOH2004
D	HOH2032
D	HOH2033
I	GLU67

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 1134

Chain	Residue
A	ASP96
A	HOH2004
A	HOH2005
A	HOH2028
A	HOH2029
G	GLU67

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG F 1134

Chain	Residue
F	ASP96
F	HOH2004
F	HOH2005
F	HOH2027
F	HOH2028
J	GLU67

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269\|PubMed:25450593

Chain	Residue	Details
G	GLU67
D	ASP96
D	ASP114
D	ASP116
E	ASP96
E	ASP114
E	ASP116
F	ASP96
F	ASP114
F	ASP116
H	GLU67
I	GLU67
J	GLU67
B	ASP114
B	ASP116
C	ASP96
C	ASP114
C	ASP116

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)