4BMK
Serine Palmitoyltransferase K265A from S. paucimobilis with bound PLP- Myriocin Aldimine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006665 | biological_process | sphingolipid metabolic process |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0006665 | biological_process | sphingolipid metabolic process |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 1423 |
| Chain | Residue |
| A | THR342 |
| A | GLU343 |
| A | THR344 |
| A | ASP346 |
| B | GLU320 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 1424 |
| Chain | Residue |
| A | ARG319 |
| A | GLU320 |
| A | TRP323 |
| A | HOH2223 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | Binding site for residues PLP A1421 and MYB A1422 |
| Chain | Residue |
| A | TYR73 |
| A | GLY134 |
| A | TYR135 |
| A | ASN138 |
| A | HIS159 |
| A | GLU202 |
| A | SER206 |
| A | ASP231 |
| A | HIS234 |
| A | THR262 |
| A | SER264 |
| A | ALA381 |
| A | HOH2153 |
| B | PHE293 |
| B | THR294 |
| B | ALA295 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | Binding site for residues PLP B1421 and MYB B1422 |
| Chain | Residue |
| A | PHE293 |
| A | THR294 |
| A | ALA295 |
| B | TYR73 |
| B | GLY134 |
| B | TYR135 |
| B | ASN138 |
| B | HIS159 |
| B | GLU202 |
| B | ASP231 |
| B | HIS234 |
| B | THR262 |
| B | SER264 |
| B | HOH2121 |
| B | HOH2254 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:17559874, ECO:0000269|PubMed:19376777, ECO:0007744|PDB:2JG2, ECO:0007744|PDB:2W8T, ECO:0007744|PDB:2W8U, ECO:0007744|PDB:2W8V |
| Chain | Residue | Details |
| A | GLY134 | |
| A | THR262 | |
| A | SER264 | |
| B | GLY134 | |
| B | THR262 | |
| B | SER264 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:17559874, ECO:0007744|PDB:2JG2 |
| Chain | Residue | Details |
| A | HIS234 | |
| B | HIS234 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-(pyridoxal phosphate)lysine => ECO:0000269|PubMed:17559874, ECO:0000269|PubMed:19376777, ECO:0007744|PDB:2JG2, ECO:0007744|PDB:2W8T, ECO:0007744|PDB:2W8U, ECO:0007744|PDB:2W8V |
| Chain | Residue | Details |
| A | ALA265 | |
| B | ALA265 |
