4BC4

Crystal structure of human D-xylulokinase in complex with D-xylulose

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004856	molecular_function	D-xylulokinase activity
A	0005524	molecular_function	ATP binding
A	0005829	cellular_component	cytosol
A	0005975	biological_process	carbohydrate metabolic process
A	0005997	biological_process	xylulose metabolic process
A	0005998	biological_process	xylulose catabolic process
A	0006091	biological_process	generation of precursor metabolites and energy
A	0016301	molecular_function	kinase activity
A	0019640	biological_process	glucuronate catabolic process to xylulose 5-phosphate
A	0042732	biological_process	D-xylose metabolic process
A	0046835	biological_process	carbohydrate phosphorylation
B	0004856	molecular_function	D-xylulokinase activity
B	0005524	molecular_function	ATP binding
B	0005829	cellular_component	cytosol
B	0005975	biological_process	carbohydrate metabolic process
B	0005997	biological_process	xylulose metabolic process
B	0005998	biological_process	xylulose catabolic process
B	0006091	biological_process	generation of precursor metabolites and energy
B	0016301	molecular_function	kinase activity
B	0019640	biological_process	glucuronate catabolic process to xylulose 5-phosphate
B	0042732	biological_process	D-xylose metabolic process
B	0046835	biological_process	carbohydrate phosphorylation
C	0004856	molecular_function	D-xylulokinase activity
C	0005524	molecular_function	ATP binding
C	0005829	cellular_component	cytosol
C	0005975	biological_process	carbohydrate metabolic process
C	0005997	biological_process	xylulose metabolic process
C	0005998	biological_process	xylulose catabolic process
C	0006091	biological_process	generation of precursor metabolites and energy
C	0016301	molecular_function	kinase activity
C	0019640	biological_process	glucuronate catabolic process to xylulose 5-phosphate
C	0042732	biological_process	D-xylose metabolic process
C	0046835	biological_process	carbohydrate phosphorylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue XUL A 1532

Chain	Residue
A	GLN97
A	GLN98
A	HIS99
A	TRP137
A	ARG170
A	ASP280
A	ASN281
A	HOH2007

---

site_id	AC2
Number of Residues	6
Details	binding site for residue EDO A 1533

Chain	Residue
A	CYS252
A	PRO324
A	VAL325
A	ASP326
A	SER327
A	SER251

---

site_id	AC3
Number of Residues	8
Details	binding site for residue XUL B 1531

Chain	Residue
B	GLN97
B	GLN98
B	HIS99
B	TRP137
B	ARG170
B	ASP280
B	ASN281
B	HOH2008

---

site_id	AC4
Number of Residues	5
Details	binding site for residue EDO B 1532

Chain	Residue
B	ILE131
B	ASP133
B	LYS178
B	HOH2065
B	HOH2093

---

site_id	AC5
Number of Residues	8
Details	binding site for residue XUL C 1531

Chain	Residue
C	GLN97
C	GLN98
C	HIS99
C	TRP137
C	ARG170
C	ASP280
C	ASN281
C	HOH2007

---

site_id	AC6
Number of Residues	7
Details	binding site for residue EDO C 1532

Chain	Residue
C	SER251
C	CYS252
C	PRO324
C	VAL325
C	ASP326
C	SER327
C	HOH2227

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	21
Details	BINDING:

Chain	Residue	Details
A	ASN281
A	TRP355
A	GLY441
A	ASN445
B	HIS99
B	ARG170
B	ASP280
B	ASN281
B	TRP355
B	GLY441
B	ASN445
C	HIS99
C	ARG170
C	ASP280
C	ASN281
C	TRP355
C	GLY441
C	ASN445
A	HIS99
A	ARG170
A	ASP280

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