4B24

Unprecedented sculpting of DNA at abasic sites by DNA glycosylase homolog Mag2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000725	biological_process	recombinational repair
A	0003677	molecular_function	DNA binding
A	0003824	molecular_function	catalytic activity
A	0003905	molecular_function	alkylbase DNA N-glycosylase activity
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0006281	biological_process	DNA repair
A	0006284	biological_process	base-excision repair
A	0006285	biological_process	base-excision repair, AP site formation
A	0006289	biological_process	nucleotide-excision repair
A	0006307	biological_process	DNA alkylation repair
A	0006974	biological_process	DNA damage response
A	0032131	molecular_function	alkylated DNA binding
A	0032993	cellular_component	protein-DNA complex
A	0140431	molecular_function	DNA-(abasic site) binding

Functional Information from PROSITE/UniProt

site_id	PS00516
Number of Residues	25
Details	ALKYLBASE_DNA_GLYCOS Alkylbase DNA glycosidases alkA family signature. GVKrWTIeMYsIftlgrldiMpaDD

Chain	Residue	Details
A	GLY138-ASP162

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:23245849, ECO:0000269|PubMed:23273506

Chain	Residue	Details
A	LYS53
A	HIS91
A	LYS97
A	LYS137
A	GLY138
A	LYS140
A	THR143
A	SER163

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site_id	SWS_FT_FI2
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:23273506

Chain	Residue	Details
A	LEU54
A	SER61
A	GLY94
A	SER96
A	LYS99
A	GLU102

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site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:23245849

Chain	Residue	Details
A	THR164

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