Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004175 | molecular_function | endopeptidase activity |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006508 | biological_process | proteolysis |
| A | 0007586 | biological_process | digestion |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0097180 | cellular_component | serine protease inhibitor complex |
| A | 0097655 | molecular_function | serpin family protein binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1246 |
| Chain | Residue |
| A | LYS169 |
| A | PRO173 |
| A | GLY174 |
| A | HOH2205 |
| A | HOH2280 |
| A | HOH2286 |
| A | HOH2296 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1247 |
| Chain | Residue |
| A | LEU99 |
| A | LYS159 |
| A | GLN175 |
| A | DMS1255 |
| A | HOH2292 |
| A | HOH2354 |
| A | HOH2357 |
| A | ASN97 |
| A | THR98 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1248 |
| Chain | Residue |
| A | HIS57 |
| A | GLN192 |
| A | GLY193 |
| A | SER195 |
| A | SW11256 |
| A | HOH2058 |
| A | HOH2327 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 1249 |
| Chain | Residue |
| A | GLU70 |
| A | ASN72 |
| A | VAL75 |
| A | GLU80 |
| A | HOH2122 |
| A | HOH2123 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 1250 |
| Chain | Residue |
| A | VAL76 |
| A | PHE82 |
| A | HOH2150 |
| A | HOH2152 |
| A | HOH2355 |
| A | HOH2356 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 1251 |
| Chain | Residue |
| A | ARG66 |
| A | ILE73 |
| A | VAL76 |
| A | VAL90 |
| A | HIS91 |
| A | PRO92 |
| A | HOH2123 |
| A | HOH2166 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 1252 |
| Chain | Residue |
| A | TYR39 |
| A | HIS40 |
| A | ILE73 |
| A | ASN74 |
| A | ILE89 |
| A | VAL90 |
| A | HOH2047 |
| A | HOH2163 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 1253 |
| Chain | Residue |
| A | CYS128 |
| A | ALA129 |
| A | PHE181 |
| A | GLN210 |
| A | LYS230 |
| A | HOH2223 |
| A | HOH2272 |
| A | HOH2326 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE DMS A 1254 |
| Chain | Residue |
| A | ASN95 |
| A | SER96 |
| A | ASN97 |
| A | HOH2170 |
| A | HOH2356 |
| site_id | BC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE DMS A 1255 |
| Chain | Residue |
| A | TYR20 |
| A | CYS22 |
| A | THR26 |
| A | ASN97 |
| A | GLN175 |
| A | SO41247 |
| A | HOH2033 |
| A | HOH2182 |
| A | HOH2292 |
| A | HOH2357 |
| site_id | BC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SW1 A 1256 |
| Chain | Residue |
| A | ASP189 |
| A | SER190 |
| A | GLN192 |
| A | SER195 |
| A | SER202 |
| A | VAL213 |
| A | GLY216 |
| A | GLY219 |
| A | SO41248 |
| A | HOH2287 |
| A | HOH2331 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| A | VAL53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPVV |
| Chain | Residue | Details |
| A | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| A | HIS57 | |
| A | ASP102 | |
| A | SER195 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLU70 | |
| A | ASN72 | |
| A | VAL75 | |
| A | GLU80 | |
| A | ASP189 | |
| A | GLN192 | |
| A | SER195 | |
