3WUI
Dimeric horse cytochrome c formed by refolding from molten globule state
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005758 | cellular_component | mitochondrial intermembrane space |
| A | 0005829 | cellular_component | cytosol |
| A | 0006122 | biological_process | mitochondrial electron transport, ubiquinol to cytochrome c |
| A | 0006123 | biological_process | mitochondrial electron transport, cytochrome c to oxygen |
| A | 0006915 | biological_process | apoptotic process |
| A | 0008289 | molecular_function | lipid binding |
| A | 0009055 | molecular_function | electron transfer activity |
| A | 0018063 | biological_process | cytochrome c-heme linkage |
| A | 0020037 | molecular_function | heme binding |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0043065 | biological_process | positive regulation of apoptotic process |
| A | 0043280 | biological_process | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0070069 | cellular_component | cytochrome complex |
| A | 0070469 | cellular_component | respirasome |
| A | 2001056 | biological_process | positive regulation of cysteine-type endopeptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEM A 201 |
| Chain | Residue |
| A | LYS13 |
| A | TYR48 |
| A | THR49 |
| A | ASN52 |
| A | TRP59 |
| A | LEU64 |
| A | TYR67 |
| A | LEU68 |
| A | THR78 |
| A | LYS79 |
| A | MET80 |
| A | CYS14 |
| A | ALA83 |
| A | PEG204 |
| A | HOH310 |
| A | HOH315 |
| A | CYS17 |
| A | HIS18 |
| A | THR28 |
| A | GLY29 |
| A | PRO30 |
| A | THR40 |
| A | GLY41 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PG4 A 202 |
| Chain | Residue |
| A | LYS55 |
| A | LYS55 |
| A | GLU66 |
| A | LYS73 |
| A | LYS73 |
| A | TYR74 |
| A | TYR74 |
| A | PRO76 |
| A | PRO76 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 A 203 |
| Chain | Residue |
| A | LYS7 |
| A | TYR97 |
| A | TYR97 |
| A | LYS100 |
| A | LYS100 |
| A | GLU104 |
| A | GLU104 |
| A | HOH321 |
| A | HOH321 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG A 204 |
| Chain | Residue |
| A | THR47 |
| A | TYR48 |
| A | THR49 |
| A | LYS79 |
| A | HEC201 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PEG A 205 |
| Chain | Residue |
| A | GLN16 |
| A | GLN16 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | BINDING: covalent |
| Chain | Residue | Details |
| A | CYS17 | |
| A | CYS14 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: axial binding residue => ECO:0000255|PROSITE-ProRule:PRU00433, ECO:0000269|PubMed:5545094 |
| Chain | Residue | Details |
| A | HIS18 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: axial binding residue |
| Chain | Residue | Details |
| A | MET80 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: N-acetylglycine => ECO:0000269|PubMed:14469771 |
| Chain | Residue | Details |
| A | GLY1 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:P62894 |
| Chain | Residue | Details |
| A | TYR97 | |
| A | TYR48 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:P62897 |
| Chain | Residue | Details |
| A | LYS55 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P62897 |
| Chain | Residue | Details |
| A | LYS72 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P62897 |
| Chain | Residue | Details |
| A | LYS99 |
