3WQZ

Crystal structure of Archaeoglobus fulgidus alanyl-tRNA synthetase in complex with a tRNA(Ala) variant having A3.U70

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000049	molecular_function	tRNA binding
A	0000166	molecular_function	nucleotide binding
A	0002161	molecular_function	aminoacyl-tRNA editing activity
A	0003676	molecular_function	nucleic acid binding
A	0004812	molecular_function	aminoacyl-tRNA ligase activity
A	0004813	molecular_function	alanine-tRNA ligase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006412	biological_process	translation
A	0006419	biological_process	alanyl-tRNA aminoacylation
A	0008270	molecular_function	zinc ion binding
A	0042802	molecular_function	identical protein binding
A	0043039	biological_process	tRNA aminoacylation
A	0045892	biological_process	negative regulation of DNA-templated transcription
A	0046872	molecular_function	metal ion binding
A	0106074	biological_process	aminoacyl-tRNA metabolism involved in translational fidelity
B	0000049	molecular_function	tRNA binding
B	0000166	molecular_function	nucleotide binding
B	0002161	molecular_function	aminoacyl-tRNA editing activity
B	0003676	molecular_function	nucleic acid binding
B	0004812	molecular_function	aminoacyl-tRNA ligase activity
B	0004813	molecular_function	alanine-tRNA ligase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006412	biological_process	translation
B	0006419	biological_process	alanyl-tRNA aminoacylation
B	0008270	molecular_function	zinc ion binding
B	0042802	molecular_function	identical protein binding
B	0043039	biological_process	tRNA aminoacylation
B	0045892	biological_process	negative regulation of DNA-templated transcription
B	0046872	molecular_function	metal ion binding
B	0106074	biological_process	aminoacyl-tRNA metabolism involved in translational fidelity

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	BINDING SITE FOR RESIDUE A5A A 1001

Chain	Residue
A	ARG128
A	ASP242
A	THR243
A	GLY244
A	GLY246
A	ARG249
A	LEU142
A	PHE145
A	MET147
A	TRP191
A	GLU209
A	VAL210
A	ALA211
A	THR212

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN A 1002

Chain	Residue
A	HIS604
A	CYS703

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site_id	AC3
Number of Residues	15
Details	BINDING SITE FOR RESIDUE A5A B 1001

Chain	Residue
B	ARG128
B	ASP131
B	HIS141
B	LEU142
B	PHE145
B	MET147
B	TRP191
B	GLU209
B	VAL210
B	ALA211
B	THR212
B	ASP242
B	THR243
B	GLY244
B	ARG249

---

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN B 1002

Chain	Residue
B	HIS600
B	HIS604
B	CYS703

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	BINDING:

Chain	Residue	Details
A	HIS600
A	HIS604
A	CYS703
A	HIS707
B	HIS600
B	HIS604
B	CYS703
B	HIS707

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