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3WBY

Crystal structure of Gox0644 D53A mutant in complex with NADPH

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0016491molecular_functionoxidoreductase activity
A0044281biological_processsmall molecule metabolic process
A0050580molecular_function2,5-didehydrogluconate reductase activity
B0000166molecular_functionnucleotide binding
B0016491molecular_functionoxidoreductase activity
B0044281biological_processsmall molecule metabolic process
B0050580molecular_function2,5-didehydrogluconate reductase activity
Functional Information from PDB Data
site_idAC1
Number of Residues18
DetailsBINDING SITE FOR RESIDUE NDP A 301
ChainResidue
AGLU31
ASER235
AVAL236
AARG240
AGLU243
AASN244
AGLY271
AALA272
BHIS20
BTHR21
ATRP113
ATRP191
AARG192
APRO193
ALEU194
ALYS196
ALEU200
ALYS234

site_idAC2
Number of Residues17
DetailsBINDING SITE FOR RESIDUE NDP B 301
ChainResidue
AHIS20
ATHR21
BTRP30
BGLU31
BTRP113
BTRP191
BARG192
BPRO193
BLEU194
BLYS196
BALA217
BLYS234
BSER235
BVAL236
BARG240
BGLU243
BASN244

Functional Information from PROSITE/UniProt
site_idPS00062
Number of Residues18
DetailsALDOKETO_REDUCTASE_2 Aldo/keto reductase family signature 2. LvelkksgrVKSIGVSNF
ChainResidueDetails
ALEU128-PHE145

site_idPS00063
Number of Residues16
DetailsALDOKETO_REDUCTASE_3 Aldo/keto reductase family putative active site signature. IPKSVNpkRLaENlDV
ChainResidueDetails
AILE232-VAL247

220113

PDB entries from 2024-05-22

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