3W2W

Crystal structure of the Cmr2dHD-Cmr3 subcomplex bound to ATP

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0000166	molecular_function	nucleotide binding
B	0003723	molecular_function	RNA binding
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0051607	biological_process	defense response to virus

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 901

Chain	Residue
A	CYS448
A	CYS451
A	CYS478
A	CYS481

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site_id	AC2
Number of Residues	18
Details	BINDING SITE FOR RESIDUE ATP A 902

Chain	Residue
A	SER246
A	LEU249
A	ASN300
A	ARG436
A	ASP600
A	TYR669
A	ASP674
A	ATP903
A	HOH1003
A	HOH1020
A	HOH1038
B	ARG262
B	MG401
A	LYS225
A	VAL227
A	VAL229
A	GLN230
A	ILE233

---

site_id	AC3
Number of Residues	18
Details	BINDING SITE FOR RESIDUE ATP A 903

Chain	Residue
A	TYR271
A	LYS301
A	ASP600
A	GLY601
A	ASP602
A	ASP603
A	MET604
A	GLY605
A	ILE608
A	HIS642
A	SER646
A	LEU649
A	LYS739
A	LYS744
A	ATP902
A	MG904
A	HOH1044
B	LYS111

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG A 904

Chain	Residue
A	ASP600
A	GLY601
A	ATP903
A	HOH1044

---

site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG B 401

Chain	Residue
A	ATP902

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:22405013, ECO:0000269|PubMed:22449983, ECO:0000269|PubMed:23395183, ECO:0000269|PubMed:23583914, ECO:0000269|PubMed:25280103

Chain	Residue	Details
A	CYS448
A	CYS451
A	CYS478
A	CYS481

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:25280103, ECO:0000305|PubMed:22405013

Chain	Residue	Details
A	ASP600
A	ASP673
A	ASP674

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:25280103

Chain	Residue	Details
A	GLU656
A	GLU694
A	GLU700

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