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3USX

Crystal structure of PGRP-S complexed with Myristic Acid at 2.28 A resolution

Functional Information from GO Data
ChainGOidnamespacecontents
A0001818biological_processnegative regulation of cytokine production
A0005576cellular_componentextracellular region
A0008270molecular_functionzinc ion binding
A0008745molecular_functionN-acetylmuramoyl-L-alanine amidase activity
A0009253biological_processpeptidoglycan catabolic process
A0016019molecular_functionpeptidoglycan immune receptor activity
A0016045biological_processdetection of bacterium
A0042742biological_processdefense response to bacterium
A0042834molecular_functionpeptidoglycan binding
A0045087biological_processinnate immune response
A0050830biological_processdefense response to Gram-positive bacterium
B0001818biological_processnegative regulation of cytokine production
B0005576cellular_componentextracellular region
B0008270molecular_functionzinc ion binding
B0008745molecular_functionN-acetylmuramoyl-L-alanine amidase activity
B0009253biological_processpeptidoglycan catabolic process
B0016019molecular_functionpeptidoglycan immune receptor activity
B0016045biological_processdetection of bacterium
B0042742biological_processdefense response to bacterium
B0042834molecular_functionpeptidoglycan binding
B0045087biological_processinnate immune response
B0050830biological_processdefense response to Gram-positive bacterium
C0001818biological_processnegative regulation of cytokine production
C0005576cellular_componentextracellular region
C0008270molecular_functionzinc ion binding
C0008745molecular_functionN-acetylmuramoyl-L-alanine amidase activity
C0009253biological_processpeptidoglycan catabolic process
C0016019molecular_functionpeptidoglycan immune receptor activity
C0016045biological_processdetection of bacterium
C0042742biological_processdefense response to bacterium
C0042834molecular_functionpeptidoglycan binding
C0045087biological_processinnate immune response
C0050830biological_processdefense response to Gram-positive bacterium
D0001818biological_processnegative regulation of cytokine production
D0005576cellular_componentextracellular region
D0008270molecular_functionzinc ion binding
D0008745molecular_functionN-acetylmuramoyl-L-alanine amidase activity
D0009253biological_processpeptidoglycan catabolic process
D0016019molecular_functionpeptidoglycan immune receptor activity
D0016045biological_processdetection of bacterium
D0042742biological_processdefense response to bacterium
D0042834molecular_functionpeptidoglycan binding
D0045087biological_processinnate immune response
D0050830biological_processdefense response to Gram-positive bacterium
Functional Information from PDB Data
site_idAC1
Number of Residues7
DetailsBINDING SITE FOR RESIDUE MYR B 172
ChainResidue
AALA129
BPRO3
BALA5
BCYS6
BLEU134
DARG31
DARG138

site_idAC2
Number of Residues7
DetailsBINDING SITE FOR RESIDUE GOL D 503
ChainResidue
DHIS37
DTHR38
DTYR71
DHIS93
DHIS146
CPRO151
DSER36

221051

PDB entries from 2024-06-12

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