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3U55

Crystal structure (Type-2) of SAICAR synthetase from Pyrococcus horikoshii OT3

Functional Information from GO Data
ChainGOidnamespacecontents
A0004639molecular_functionphosphoribosylaminoimidazolesuccinocarboxamide synthase activity
A0005524molecular_functionATP binding
A0005829cellular_componentcytosol
A0006164biological_processpurine nucleotide biosynthetic process
A0006189biological_process'de novo' IMP biosynthetic process
A0009236biological_processcobalamin biosynthetic process
A0016874molecular_functionligase activity
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE SO4 A 500
ChainResidue
AARG93
AGLY98
ASER99
AARG198
AHOH429

site_idAC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE SO4 A 501
ChainResidue
AHOH403
ATHR32
APHE34
ALYS210
AARG214

site_idAC3
Number of Residues5
DetailsBINDING SITE FOR RESIDUE ACT A 502
ChainResidue
AARG103
AARG103
APRO129
AMET130
AHOH286

Functional Information from PROSITE/UniProt
site_idPS01057
Number of Residues15
DetailsSAICAR_SYNTHETASE_1 SAICAR synthetase signature 1. MYPLEvVVRnvvAGS
ChainResidueDetails
AMET85-SER99

site_idPS01058
Number of Residues9
DetailsSAICAR_SYNTHETASE_2 SAICAR synthetase signature 2. LVDfKLEFG
ChainResidueDetails
ALEU171-GLY179

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PDB entries from 2024-05-29

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