3TFX
Crystal structure of Orotidine 5'-phosphate decarboxylase from Lactobacillus acidophilus
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004590 | molecular_function | orotidine-5'-phosphate decarboxylase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| A | 0006221 | biological_process | pyrimidine nucleotide biosynthetic process |
| A | 0016831 | molecular_function | carboxy-lyase activity |
| A | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
| B | 0004590 | molecular_function | orotidine-5'-phosphate decarboxylase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| B | 0006221 | biological_process | pyrimidine nucleotide biosynthetic process |
| B | 0016831 | molecular_function | carboxy-lyase activity |
| B | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
Functional Information from PROSITE/UniProt
| site_id | PS00156 |
| Number of Residues | 14 |
| Details | OMPDECASE Orotidine 5'-phosphate decarboxylase active site. IFlDlKmhDIPnTV |
| Chain | Residue | Details |
| A | ILE57-VAL70 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor => ECO:0000255|HAMAP-Rule:MF_01200 |
| Chain | Residue | Details |
| A | LYS62 | |
| B | LYS62 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01200 |
| Chain | Residue | Details |
| B | ARG185 | |
| B | GLN194 | |
| B | GLY214 | |
| B | ARG215 | |
| A | ARG215 | |
| A | ASP10 | |
| A | LYS33 | |
| A | ASP60 | |
| A | THR123 | |
| A | ARG185 | |
| A | GLN194 | |
| A | GLY214 | |
| B | ASP10 | |
| B | LYS33 | |
| B | ASP60 | |
| B | THR123 |
