3SLC

Crystal structure of apo form of acetate kinase (AckA) from Salmonella typhimurium

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006082	biological_process	organic acid metabolic process
A	0006083	biological_process	acetate metabolic process
A	0006085	biological_process	acetyl-CoA biosynthetic process
A	0008776	molecular_function	acetate kinase activity
A	0008980	molecular_function	propionate kinase activity
A	0016301	molecular_function	kinase activity
A	0016310	biological_process	phosphorylation
A	0016774	molecular_function	phosphotransferase activity, carboxyl group as acceptor
A	0046872	molecular_function	metal ion binding
A	0047900	molecular_function	formate kinase activity
B	0000287	molecular_function	magnesium ion binding
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006082	biological_process	organic acid metabolic process
B	0006083	biological_process	acetate metabolic process
B	0006085	biological_process	acetyl-CoA biosynthetic process
B	0008776	molecular_function	acetate kinase activity
B	0008980	molecular_function	propionate kinase activity
B	0016301	molecular_function	kinase activity
B	0016310	biological_process	phosphorylation
B	0016774	molecular_function	phosphotransferase activity, carboxyl group as acceptor
B	0046872	molecular_function	metal ion binding
B	0047900	molecular_function	formate kinase activity
C	0000287	molecular_function	magnesium ion binding
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006082	biological_process	organic acid metabolic process
C	0006083	biological_process	acetate metabolic process
C	0006085	biological_process	acetyl-CoA biosynthetic process
C	0008776	molecular_function	acetate kinase activity
C	0008980	molecular_function	propionate kinase activity
C	0016301	molecular_function	kinase activity
C	0016310	biological_process	phosphorylation
C	0016774	molecular_function	phosphotransferase activity, carboxyl group as acceptor
C	0046872	molecular_function	metal ion binding
C	0047900	molecular_function	formate kinase activity
D	0000287	molecular_function	magnesium ion binding
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006082	biological_process	organic acid metabolic process
D	0006083	biological_process	acetate metabolic process
D	0006085	biological_process	acetyl-CoA biosynthetic process
D	0008776	molecular_function	acetate kinase activity
D	0008980	molecular_function	propionate kinase activity
D	0016301	molecular_function	kinase activity
D	0016310	biological_process	phosphorylation
D	0016774	molecular_function	phosphotransferase activity, carboxyl group as acceptor
D	0046872	molecular_function	metal ion binding
D	0047900	molecular_function	formate kinase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 504

Chain	Residue
A	ASN267
A	HOH453
B	PHE253

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO B 501

Chain	Residue
B	GLU388
B	HOH458

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO B 502

Chain	Residue
B	THR242
B	ARG243
B	GLY212
B	GLY214
B	MET240
B	GLY241

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO D 503

Chain	Residue
D	LYS142
D	ASP143

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Functional Information from PROSITE/UniProt

site_id	PS01075
Number of Residues	12
Details	ACETATE_KINASE_1 Acetate and butyrate kinases family signature 1. VLvLNcGSSSlK

Chain	Residue	Details
A	VAL6-LYS17

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site_id	PS01076
Number of Residues	18
Details	ACETATE_KINASE_2 Acetate and butyrate kinases family signature 2. IItcHlGnGgSVsAirnG

Chain	Residue	Details
A	ILE206-GLY223

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_00020

Chain	Residue	Details
A	ASP150
B	ASP150
C	ASP150
D	ASP150

---

site_id	SWS_FT_FI2
Number of Residues	28
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00020

Chain	Residue	Details
A	ASP285
A	GLY333
A	GLU387
B	ASN10
B	LYS17
B	ARG91
B	HIS210
B	ASP285
B	GLY333
B	GLU387
C	ASN10
C	LYS17
C	ARG91
C	HIS210
C	ASP285
C	GLY333
C	GLU387
D	ASN10
D	LYS17
D	ARG91
D	HIS210
D	ASP285
D	GLY333
D	GLU387
A	ASN10
A	LYS17
A	ARG91
A	HIS210

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site_id	SWS_FT_FI3
Number of Residues	8
Details	SITE: Transition state stabilizer => ECO:0000255|HAMAP-Rule:MF_00020

Chain	Residue	Details
C	ARG243
D	HIS182
D	ARG243
A	HIS182
A	ARG243
B	HIS182
B	ARG243
C	HIS182

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