3RDZ
Crystal Structure of rBTI-trypsin complex at 2.26 angstrom resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004175 | molecular_function | endopeptidase activity |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006508 | biological_process | proteolysis |
| A | 0007586 | biological_process | digestion |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0097180 | cellular_component | serine protease inhibitor complex |
| A | 0097655 | molecular_function | serpin family protein binding |
| B | 0004175 | molecular_function | endopeptidase activity |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005615 | cellular_component | extracellular space |
| B | 0006508 | biological_process | proteolysis |
| B | 0007586 | biological_process | digestion |
| B | 0008236 | molecular_function | serine-type peptidase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0097180 | cellular_component | serine protease inhibitor complex |
| B | 0097655 | molecular_function | serpin family protein binding |
| C | 0004867 | molecular_function | serine-type endopeptidase inhibitor activity |
| C | 0009611 | biological_process | response to wounding |
| D | 0004867 | molecular_function | serine-type endopeptidase inhibitor activity |
| D | 0009611 | biological_process | response to wounding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 1 |
| Chain | Residue |
| A | HOH9 |
| A | HOH17 |
| A | GLU70 |
| A | ASN72 |
| A | VAL75 |
| A | GLU80 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 1 |
| Chain | Residue |
| B | VAL75 |
| B | GLU80 |
| B | HOH336 |
| B | HOH6 |
| B | GLU70 |
| B | ASN72 |
Functional Information from PROSITE/UniProt
| site_id | PS00285 |
| Number of Residues | 12 |
| Details | POTATO_INHIBITOR Potato inhibitor I family signature. WPELVGerGskA |
| Chain | Residue | Details |
| C | TRP10-ALA21 |
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| A | VAL54-CYS59 |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPVV |
| Chain | Residue | Details |
| A | ASP189-VAL200 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| A | HIS58 | |
| A | ASP102 | |
| A | SER195 | |
| B | HIS58 | |
| B | ASP102 | |
| B | SER195 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 14 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLU70 | |
| B | VAL75 | |
| B | GLU80 | |
| B | ASP189 | |
| B | GLN192 | |
| B | SER195 | |
| A | ASN72 | |
| A | VAL75 | |
| A | GLU80 | |
| A | ASP189 | |
| A | GLN192 | |
| A | SER195 | |
| B | GLU70 | |
| B | ASN72 |
