3QNA

Crystal structure of a 6-pyruvoyltetrahydropterin synthase homologue from Esherichia coli complexed sepiapterin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008616	biological_process	queuosine biosynthetic process
A	0016829	molecular_function	lyase activity
A	0046872	molecular_function	metal ion binding
A	0070497	molecular_function	6-carboxy-5,6,7,8-tetrahydropterin synthase activity
B	0008616	biological_process	queuosine biosynthetic process
B	0016829	molecular_function	lyase activity
B	0046872	molecular_function	metal ion binding
B	0070497	molecular_function	6-carboxy-5,6,7,8-tetrahydropterin synthase activity
C	0008616	biological_process	queuosine biosynthetic process
C	0016829	molecular_function	lyase activity
C	0046872	molecular_function	metal ion binding
C	0070497	molecular_function	6-carboxy-5,6,7,8-tetrahydropterin synthase activity
D	0008616	biological_process	queuosine biosynthetic process
D	0016829	molecular_function	lyase activity
D	0046872	molecular_function	metal ion binding
D	0070497	molecular_function	6-carboxy-5,6,7,8-tetrahydropterin synthase activity
E	0008616	biological_process	queuosine biosynthetic process
E	0016829	molecular_function	lyase activity
E	0046872	molecular_function	metal ion binding
E	0070497	molecular_function	6-carboxy-5,6,7,8-tetrahydropterin synthase activity
F	0008616	biological_process	queuosine biosynthetic process
F	0016829	molecular_function	lyase activity
F	0046872	molecular_function	metal ion binding
F	0070497	molecular_function	6-carboxy-5,6,7,8-tetrahydropterin synthase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	17
Details	BINDING SITE FOR RESIDUE BIO A 121

Chain	Residue
A	HIS15
A	GLU109
A	ZN122
B	LEU5
B	TRP50
B	ILE52
B	ASP53
B	PHE54
D	HIS70
A	LEU17
A	LYS25
A	ALA26
A	HIS30
A	HIS32
A	THR83
A	SER84
A	GLU85

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 122

Chain	Residue
A	HIS15
A	HIS30
A	HIS32
A	BIO121

---

site_id	AC3
Number of Residues	16
Details	BINDING SITE FOR RESIDUE BIO B 121

Chain	Residue
B	HIS15
B	LYS25
B	ALA26
B	HIS30
B	HIS32
B	THR83
B	SER84
B	GLU85
B	GLU109
B	ZN122
C	LEU5
C	TRP50
C	ILE52
C	ASP53
C	PHE54
F	HIS70

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 122

Chain	Residue
B	HIS15
B	HIS30
B	HIS32
B	BIO121

---

site_id	AC5
Number of Residues	15
Details	BINDING SITE FOR RESIDUE BIO C 121

Chain	Residue
A	TRP50
A	ILE52
A	ASP53
A	PHE54
C	HIS15
C	LEU17
C	ALA26
C	HIS30
C	HIS32
C	THR83
C	SER84
C	GLU85
C	GLU109
C	ZN122
E	HIS70

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 122

Chain	Residue
C	HIS15
C	HIS30
C	HIS32
C	BIO121

---

site_id	AC7
Number of Residues	16
Details	BINDING SITE FOR RESIDUE BIO D 121

Chain	Residue
A	HIS70
D	HIS15
D	LYS25
D	ALA26
D	HIS30
D	HIS32
D	THR83
D	SER84
D	GLU85
D	GLU109
D	ZN122
E	LEU5
E	TRP50
E	ILE52
E	ASP53
E	PHE54

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 122

Chain	Residue
D	HIS15
D	HIS30
D	HIS32
D	BIO121

---

site_id	AC9
Number of Residues	14
Details	BINDING SITE FOR RESIDUE BIO E 121

Chain	Residue
C	HIS70
E	HIS15
E	ALA26
E	HIS30
E	HIS32
E	THR83
E	SER84
E	GLU85
E	GLU109
E	ZN122
F	TRP50
F	ILE52
F	ASP53
F	PHE54

---

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN E 122

Chain	Residue
E	HIS15
E	HIS30
E	HIS32
E	BIO121

---

site_id	BC2
Number of Residues	17
Details	BINDING SITE FOR RESIDUE BIO F 121

Chain	Residue
D	LEU5
D	TRP50
D	ILE52
D	ASP53
D	PHE54
F	HIS15
F	LEU17
F	LYS25
F	ALA26
F	HIS30
F	HIS32
F	THR83
F	SER84
F	GLU85
F	GLU109
F	ZN122
B	HIS70

---

site_id	BC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN F 122

Chain	Residue
F	HIS15
F	HIS30
F	HIS32
F	GLU109
F	BIO121

---