3QB5

Human C3PO complex in the presence of MnSO4

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001673	cellular_component	male germ cell nucleus
A	0003677	molecular_function	DNA binding
A	0003697	molecular_function	single-stranded DNA binding
A	0003723	molecular_function	RNA binding
A	0003729	molecular_function	mRNA binding
A	0004519	molecular_function	endonuclease activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005783	cellular_component	endoplasmic reticulum
A	0005829	cellular_component	cytosol
A	0006310	biological_process	DNA recombination
A	0016070	biological_process	RNA metabolic process
A	0030422	biological_process	siRNA processing
A	0035194	biological_process	regulatory ncRNA-mediated post-transcriptional gene silencing
A	0042802	molecular_function	identical protein binding
A	0043565	molecular_function	sequence-specific DNA binding
A	1902555	cellular_component	endoribonuclease complex
B	0001673	cellular_component	male germ cell nucleus
B	0003677	molecular_function	DNA binding
B	0003697	molecular_function	single-stranded DNA binding
B	0003723	molecular_function	RNA binding
B	0003729	molecular_function	mRNA binding
B	0004519	molecular_function	endonuclease activity
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0005783	cellular_component	endoplasmic reticulum
B	0005829	cellular_component	cytosol
B	0006310	biological_process	DNA recombination
B	0016070	biological_process	RNA metabolic process
B	0030422	biological_process	siRNA processing
B	0035194	biological_process	regulatory ncRNA-mediated post-transcriptional gene silencing
B	0042802	molecular_function	identical protein binding
B	0043565	molecular_function	sequence-specific DNA binding
B	1902555	cellular_component	endoribonuclease complex
C	0001673	cellular_component	male germ cell nucleus
C	0003677	molecular_function	DNA binding
C	0003697	molecular_function	single-stranded DNA binding
C	0003723	molecular_function	RNA binding
C	0003729	molecular_function	mRNA binding
C	0004519	molecular_function	endonuclease activity
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005737	cellular_component	cytoplasm
C	0005783	cellular_component	endoplasmic reticulum
C	0005829	cellular_component	cytosol
C	0006310	biological_process	DNA recombination
C	0016070	biological_process	RNA metabolic process
C	0030422	biological_process	siRNA processing
C	0035194	biological_process	regulatory ncRNA-mediated post-transcriptional gene silencing
C	0042802	molecular_function	identical protein binding
C	0043565	molecular_function	sequence-specific DNA binding
C	1902555	cellular_component	endoribonuclease complex
K	0003677	molecular_function	DNA binding
K	0003697	molecular_function	single-stranded DNA binding
K	0003723	molecular_function	RNA binding
K	0004521	molecular_function	RNA endonuclease activity
K	0005634	cellular_component	nucleus
K	0005654	cellular_component	nucleoplasm
K	0005737	cellular_component	cytoplasm
K	0005794	cellular_component	Golgi apparatus
K	0005829	cellular_component	cytosol
K	0007283	biological_process	spermatogenesis
K	0030154	biological_process	cell differentiation
K	0030422	biological_process	siRNA processing
K	0031687	molecular_function	A2A adenosine receptor binding
K	0035194	biological_process	regulatory ncRNA-mediated post-transcriptional gene silencing
K	0043565	molecular_function	sequence-specific DNA binding
K	0044877	molecular_function	protein-containing complex binding
K	0046872	molecular_function	metal ion binding
K	0048471	cellular_component	perinuclear region of cytoplasm
K	1902555	cellular_component	endoribonuclease complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NA A 229

Chain	Residue
A	ASP136

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PO4 C 229

Chain	Residue
C	LYS187
C	ASN188
K	ARG61
K	LYS68

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site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL C 230

Chain	Residue
C	ARG215
K	LYS269

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site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MN K 291

Chain	Residue
K	SO4294
K	GLU129
K	GLU197

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site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PO4 K 292

Chain	Residue
C	ASP196
C	LYS199
C	TYR200
K	MET199
K	LYS252

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site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE SO4 K 293

Chain	Residue
K	ARG200

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site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 K 294

Chain	Residue
C	ASN188
C	ARG192
K	LYS68
K	GLU126
K	MN291

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING:

Chain	Residue	Details
K	GLU129
K	GLU197
B	LYS187
B	LYS199
C	LYS187
C	LYS199

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site_id	SWS_FT_FI2
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
K	LYS279
B	SER190
C	SER190

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