3OP1
Crystal Structure of Macrolide-efflux Protein SP_1110 from Streptococcus pneumoniae
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003919 | molecular_function | FMN adenylyltransferase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006747 | biological_process | FAD biosynthetic process |
| A | 0006771 | biological_process | riboflavin metabolic process |
| A | 0008531 | molecular_function | riboflavin kinase activity |
| A | 0009231 | biological_process | riboflavin biosynthetic process |
| A | 0009398 | biological_process | FMN biosynthetic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| B | 0003919 | molecular_function | FMN adenylyltransferase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006747 | biological_process | FAD biosynthetic process |
| B | 0006771 | biological_process | riboflavin metabolic process |
| B | 0008531 | molecular_function | riboflavin kinase activity |
| B | 0009231 | biological_process | riboflavin biosynthetic process |
| B | 0009398 | biological_process | FMN biosynthetic process |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016779 | molecular_function | nucleotidyltransferase activity |
| C | 0003919 | molecular_function | FMN adenylyltransferase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0006747 | biological_process | FAD biosynthetic process |
| C | 0006771 | biological_process | riboflavin metabolic process |
| C | 0008531 | molecular_function | riboflavin kinase activity |
| C | 0009231 | biological_process | riboflavin biosynthetic process |
| C | 0009398 | biological_process | FMN biosynthetic process |
| C | 0016301 | molecular_function | kinase activity |
| C | 0016779 | molecular_function | nucleotidyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 311 |
| Chain | Residue |
| A | TYR25 |
| A | HIS30 |
| A | HIS33 |
| A | SER163 |
| A | SER164 |
| A | HOH343 |
| A | HOH361 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 312 |
| Chain | Residue |
| A | VAL152 |
| A | PRO153 |
| A | PRO154 |
| A | VAL155 |
| A | ILE162 |
| A | HOH387 |
| A | GLY32 |
| A | GLY126 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG A 314 |
| Chain | Residue |
| A | LEU64 |
| A | PRO66 |
| A | HOH390 |
| B | HIS195 |
| C | LYS159 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 315 |
| Chain | Residue |
| A | ASP260 |
| A | ARG302 |
| A | HOH370 |
| C | ARG38 |
| C | ASN41 |
| C | GLU88 |
| C | HOH364 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACY A 316 |
| Chain | Residue |
| A | LYS61 |
| A | ASP70 |
| A | ARG168 |
| A | TYR217 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 317 |
| Chain | Residue |
| A | GLU58 |
| A | HIS74 |
| A | PRO78 |
| A | ARG215 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 318 |
| Chain | Residue |
| A | GLY24 |
| A | TYR25 |
| A | MSE54 |
| A | TYR129 |
| A | HOH320 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG A 319 |
| Chain | Residue |
| A | PHE72 |
| A | ARG215 |
| A | HOH375 |
| B | CL306 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 313 |
| Chain | Residue |
| A | GLY180 |
| A | PRO186 |
| B | PHE247 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 311 |
| Chain | Residue |
| B | HIS30 |
| B | HIS33 |
| B | SER163 |
| B | SER164 |
| B | HOH399 |
| B | HOH400 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 312 |
| Chain | Residue |
| B | ASP285 |
| B | GLN289 |
| C | LYS42 |
| site_id | BC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 306 |
| Chain | Residue |
| A | PEG319 |
| B | PEG314 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PEG B 314 |
| Chain | Residue |
| A | LEU212 |
| B | PRO69 |
| B | PHE72 |
| B | ARG215 |
| B | CL306 |
| B | HOH398 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 315 |
| Chain | Residue |
| B | ARG199 |
| B | THR282 |
| B | LYS283 |
| B | PHE284 |
| site_id | BC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL B 316 |
| Chain | Residue |
| B | SER59 |
| B | LYS61 |
| site_id | BC7 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PEG B 317 |
| Chain | Residue |
| B | GLY24 |
| B | MSE54 |
| B | PHE102 |
| B | PHE110 |
| B | TYR129 |
| B | THR130 |
| B | PHE131 |
| B | GLY132 |
| B | HOH370 |
| B | HOH375 |
| B | HOH387 |
| site_id | BC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 C 311 |
| Chain | Residue |
| C | TYR25 |
| C | HIS30 |
| C | HIS33 |
| C | LYS161 |
| C | SER163 |
| C | SER164 |
| C | GOL314 |
| C | HOH329 |
| site_id | BC9 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL C 312 |
| Chain | Residue |
| C | HIS30 |
| C | GLY32 |
| C | GLY126 |
| C | PHE127 |
| C | VAL152 |
| C | PRO153 |
| C | PRO154 |
| C | VAL155 |
| C | LYS161 |
| C | HOH330 |
| site_id | CC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL C 313 |
| Chain | Residue |
| C | GLY24 |
| C | TYR25 |
| C | MSE54 |
| C | TYR129 |
| C | HOH338 |
| C | HOH342 |
| site_id | CC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL C 314 |
| Chain | Residue |
| C | ASP128 |
| C | TYR129 |
| C | SO4311 |
| C | HOH370 |
| site_id | CC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL C 315 |
| Chain | Residue |
| C | PRO69 |
| C | PHE72 |
| C | VAL211 |
| C | ARG215 |
| site_id | CC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL C 316 |
| Chain | Residue |
| C | TYR25 |
| C | PHE56 |
| C | HIS74 |
| C | ARG81 |
| C | HOH366 |
