Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3NBU

Crystal structure of pGI glucosephosphate isomerase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004347	molecular_function	glucose-6-phosphate isomerase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006094	biological_process	gluconeogenesis
A	0006096	biological_process	glycolytic process
A	0016853	molecular_function	isomerase activity
A	0034599	biological_process	cellular response to oxidative stress
A	0042802	molecular_function	identical protein binding
A	0042803	molecular_function	protein homodimerization activity
A	0048029	molecular_function	monosaccharide binding
A	0051156	biological_process	glucose 6-phosphate metabolic process
A	0097367	molecular_function	carbohydrate derivative binding
A	1901135	biological_process	carbohydrate derivative metabolic process
B	0004347	molecular_function	glucose-6-phosphate isomerase activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006094	biological_process	gluconeogenesis
B	0006096	biological_process	glycolytic process
B	0016853	molecular_function	isomerase activity
B	0034599	biological_process	cellular response to oxidative stress
B	0042802	molecular_function	identical protein binding
B	0042803	molecular_function	protein homodimerization activity
B	0048029	molecular_function	monosaccharide binding
B	0051156	biological_process	glucose 6-phosphate metabolic process
B	0097367	molecular_function	carbohydrate derivative binding
B	1901135	biological_process	carbohydrate derivative metabolic process
C	0004347	molecular_function	glucose-6-phosphate isomerase activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006094	biological_process	gluconeogenesis
C	0006096	biological_process	glycolytic process
C	0016853	molecular_function	isomerase activity
C	0034599	biological_process	cellular response to oxidative stress
C	0042802	molecular_function	identical protein binding
C	0042803	molecular_function	protein homodimerization activity
C	0048029	molecular_function	monosaccharide binding
C	0051156	biological_process	glucose 6-phosphate metabolic process
C	0097367	molecular_function	carbohydrate derivative binding
C	1901135	biological_process	carbohydrate derivative metabolic process
D	0004347	molecular_function	glucose-6-phosphate isomerase activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006094	biological_process	gluconeogenesis
D	0006096	biological_process	glycolytic process
D	0016853	molecular_function	isomerase activity
D	0034599	biological_process	cellular response to oxidative stress
D	0042802	molecular_function	identical protein binding
D	0042803	molecular_function	protein homodimerization activity
D	0048029	molecular_function	monosaccharide binding
D	0051156	biological_process	glucose 6-phosphate metabolic process
D	0097367	molecular_function	carbohydrate derivative binding
D	1901135	biological_process	carbohydrate derivative metabolic process
E	0004347	molecular_function	glucose-6-phosphate isomerase activity
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006094	biological_process	gluconeogenesis
E	0006096	biological_process	glycolytic process
E	0016853	molecular_function	isomerase activity
E	0034599	biological_process	cellular response to oxidative stress
E	0042802	molecular_function	identical protein binding
E	0042803	molecular_function	protein homodimerization activity
E	0048029	molecular_function	monosaccharide binding
E	0051156	biological_process	glucose 6-phosphate metabolic process
E	0097367	molecular_function	carbohydrate derivative binding
E	1901135	biological_process	carbohydrate derivative metabolic process
F	0004347	molecular_function	glucose-6-phosphate isomerase activity
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006094	biological_process	gluconeogenesis
F	0006096	biological_process	glycolytic process
F	0016853	molecular_function	isomerase activity
F	0034599	biological_process	cellular response to oxidative stress
F	0042802	molecular_function	identical protein binding
F	0042803	molecular_function	protein homodimerization activity
F	0048029	molecular_function	monosaccharide binding
F	0051156	biological_process	glucose 6-phosphate metabolic process
F	0097367	molecular_function	carbohydrate derivative binding
F	1901135	biological_process	carbohydrate derivative metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL D 550

Chain	Residue
D	ARG94
D	ALA95
D	ASP265
D	TRP266
D	HOH1133

Functional Information from PROSITE/UniProt

site_id	PS00174
Number of Residues	18
Details	P_GLUCOSE_ISOMERASE_2 Phosphoglucose isomerase signature 2. GvILniftFDQwGVElgK

Chain	Residue	Details
A	GLY497-LYS514

site_id	PS00765
Number of Residues	14
Details	P_GLUCOSE_ISOMERASE_1 Phosphoglucose isomerase signature 1. DwVGGRYSLwSAIG

Chain	Residue	Details
A	ASP265-GLY278

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	ACT_SITE: Proton donor => ECO:0000255\|HAMAP-Rule:MF_00473

Chain	Residue	Details
A	GLU355
B	GLU355
C	GLU355
D	GLU355
E	GLU355
F	GLU355

site_id	SWS_FT_FI2
Number of Residues	12
Details	ACT_SITE: ACT_SITE => ECO:0000255\|HAMAP-Rule:MF_00473

Chain	Residue	Details
A	HIS386
A	LYS514
B	HIS386
B	LYS514
C	HIS386
C	LYS514
D	HIS386
D	LYS514
E	HIS386
E	LYS514
F	HIS386
F	LYS514

site_id	SWS_FT_FI3
Number of Residues	18
Details	MOD_RES: N6-acetyllysine => ECO:0000255\|HAMAP-Rule:MF_00473, ECO:0000269\|PubMed:18723842

Chain	Residue	Details
A	LYS80
A	LYS228
A	LYS234
B	LYS80
B	LYS228
B	LYS234
C	LYS80
C	LYS228
C	LYS234
D	LYS80
D	LYS228
D	LYS234
E	LYS80
E	LYS228
E	LYS234
F	LYS80
F	LYS228
F	LYS234

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)