Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004517 | molecular_function | nitric-oxide synthase activity |
| A | 0006809 | biological_process | nitric oxide biosynthetic process |
| B | 0004517 | molecular_function | nitric-oxide synthase activity |
| B | 0006809 | biological_process | nitric oxide biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE HEM A 500 |
| Chain | Residue |
| A | TRP180 |
| A | TYR477 |
| A | H4B600 |
| A | XFM800 |
| A | HOH1001 |
| A | ARG185 |
| A | CYS186 |
| A | SER228 |
| A | PHE355 |
| A | SER356 |
| A | GLY357 |
| A | TRP358 |
| A | GLU363 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT A 850 |
| Chain | Residue |
| A | ARG252 |
| A | ASN368 |
| A | ARG374 |
| A | HOH1044 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACT A 860 |
| Chain | Residue |
| A | TRP358 |
| A | SER428 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 880 |
| Chain | Residue |
| A | ARG367 |
| A | HIS373 |
| A | TRP449 |
| A | H4B600 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE XFM A 800 |
| Chain | Residue |
| A | VAL338 |
| A | ASN340 |
| A | PHE355 |
| A | GLY357 |
| A | TRP358 |
| A | TYR359 |
| A | GLU363 |
| A | TYR477 |
| A | HEM500 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CAD A 950 |
| Chain | Residue |
| A | THR85 |
| A | CYS384 |
| A | ARG440 |
| A | GLY441 |
| site_id | AC7 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE H4B A 600 |
| Chain | Residue |
| A | SER104 |
| A | ARG367 |
| A | ALA448 |
| A | TRP449 |
| A | HEM500 |
| A | GOL880 |
| A | HOH1061 |
| B | TRP447 |
| B | PHE462 |
| B | HIS463 |
| B | GLN464 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 900 |
| Chain | Residue |
| A | CYS96 |
| A | CYS101 |
| B | CYS96 |
| B | CYS101 |
| site_id | AC9 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE HEM B 500 |
| Chain | Residue |
| B | TRP180 |
| B | ALA183 |
| B | CYS186 |
| B | SER228 |
| B | PHE355 |
| B | SER356 |
| B | GLY357 |
| B | TRP358 |
| B | MET360 |
| B | TRP449 |
| B | TYR477 |
| B | H4B600 |
| B | XFM800 |
| B | GOL890 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT B 850 |
| Chain | Residue |
| B | ARG252 |
| B | ASN368 |
| B | ARG374 |
| B | HOH1073 |
| site_id | BC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACT B 860 |
| Chain | Residue |
| B | TRP358 |
| B | SER428 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 880 |
| Chain | Residue |
| B | ARG367 |
| B | H4B600 |
| B | GOL890 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CAD B 950 |
| Chain | Residue |
| B | TRP324 |
| B | ASP380 |
| B | CYS384 |
| site_id | BC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE H4B B 600 |
| Chain | Residue |
| A | TRP447 |
| A | PHE462 |
| A | HIS463 |
| B | SER104 |
| B | ARG367 |
| B | ALA448 |
| B | TRP449 |
| B | HEM500 |
| B | GOL880 |
| site_id | BC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE XFM B 800 |
| Chain | Residue |
| B | VAL338 |
| B | MET341 |
| B | PHE355 |
| B | TRP358 |
| B | TYR359 |
| B | GLU363 |
| B | TYR477 |
| B | HEM500 |
| B | GOL890 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 890 |
| Chain | Residue |
| B | TRP449 |
| B | HEM500 |
| B | XFM800 |
| B | GOL880 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 1 |
| Chain | Residue |
| A | GLU77 |
| B | ASP371 |
| B | HIS373 |
| B | HOH1131 |
Functional Information from PROSITE/UniProt
| site_id | PS60001 |
| Number of Residues | 8 |
| Details | NOS Nitric oxide synthase (NOS) signature. RCVGRIqW |
| Chain | Residue | Details |
| A | ARG185-TRP192 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | CYS96 | |
| A | CYS101 | |
| B | CYS96 | |
| B | CYS101 | |
| Chain | Residue | Details |
| A | SER104 | |
| A | TYR477 | |
| B | SER104 | |
| B | GLN249 | |
| B | TRP358 | |
| B | TYR359 | |
| B | GLU363 | |
| B | ASN368 | |
| B | ALA448 | |
| B | TRP449 | |
| B | PHE462 | |
| A | GLN249 | |
| B | TYR477 | |
| A | TRP358 | |
| A | TYR359 | |
| A | GLU363 | |
| A | ASN368 | |
| A | ALA448 | |
| A | TRP449 | |
| A | PHE462 | |
| Chain | Residue | Details |
| A | CYS186 | |
| B | CYS186 | |
| Chain | Residue | Details |
| A | SER116 | |
| B | SER116 | |
