Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3MHG

Dihydroxyacetone phosphate carbanion intermediate in tagatose-1,6-bisphosphate aldolase from Streptococcus pyogenes

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0005988	biological_process	lactose metabolic process
A	0009024	molecular_function	tagatose-6-phosphate kinase activity
A	0009025	molecular_function	tagatose-bisphosphate aldolase activity
A	0016829	molecular_function	lyase activity
A	0019512	biological_process	lactose catabolic process via tagatose-6-phosphate
A	0061595	molecular_function	6-deoxy-6-sulfofructose-1-phosphate aldolase activity
A	1902777	biological_process	6-sulfoquinovose(1-) catabolic process
A	2001059	biological_process	D-tagatose 6-phosphate catabolic process
B	0003824	molecular_function	catalytic activity
B	0005988	biological_process	lactose metabolic process
B	0009024	molecular_function	tagatose-6-phosphate kinase activity
B	0009025	molecular_function	tagatose-bisphosphate aldolase activity
B	0016829	molecular_function	lyase activity
B	0019512	biological_process	lactose catabolic process via tagatose-6-phosphate
B	0061595	molecular_function	6-deoxy-6-sulfofructose-1-phosphate aldolase activity
B	1902777	biological_process	6-sulfoquinovose(1-) catabolic process
B	2001059	biological_process	D-tagatose 6-phosphate catabolic process
C	0003824	molecular_function	catalytic activity
C	0005988	biological_process	lactose metabolic process
C	0009024	molecular_function	tagatose-6-phosphate kinase activity
C	0009025	molecular_function	tagatose-bisphosphate aldolase activity
C	0016829	molecular_function	lyase activity
C	0019512	biological_process	lactose catabolic process via tagatose-6-phosphate
C	0061595	molecular_function	6-deoxy-6-sulfofructose-1-phosphate aldolase activity
C	1902777	biological_process	6-sulfoquinovose(1-) catabolic process
C	2001059	biological_process	D-tagatose 6-phosphate catabolic process
D	0003824	molecular_function	catalytic activity
D	0005988	biological_process	lactose metabolic process
D	0009024	molecular_function	tagatose-6-phosphate kinase activity
D	0009025	molecular_function	tagatose-bisphosphate aldolase activity
D	0016829	molecular_function	lyase activity
D	0019512	biological_process	lactose catabolic process via tagatose-6-phosphate
D	0061595	molecular_function	6-deoxy-6-sulfofructose-1-phosphate aldolase activity
D	1902777	biological_process	6-sulfoquinovose(1-) catabolic process
D	2001059	biological_process	D-tagatose 6-phosphate catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE 13P A 3001

Chain	Residue
A	ASP27
A	GLY277
A	ARG278
A	HOH516
A	GLN28
A	LEU68
A	LYS125
A	GLU163
A	LYS205
A	SER249
A	ALA250
A	LEU275

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CA A 327

Chain	Residue
C	HOH346
C	HOH352
C	HOH397
C	HOH413
C	HOH414
C	HOH446
C	HOH1940

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CA A 328

Chain	Residue
A	HOH554
A	HOH557
A	HOH558
A	HOH560
A	HOH561
A	HOH1835
C	HOH379

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA A 329

Chain	Residue
A	GLU238
A	THR241
A	HOH1268
C	GLU83
C	GLU84

site_id	AC5
Number of Residues	14
Details	BINDING SITE FOR RESIDUE 13P B 3002

Chain	Residue
B	ASP27
B	GLN28
B	LEU68
B	LYS125
B	GLU163
B	LYS205
B	LEU248
B	SER249
B	ALA250
B	LEU275
B	GLY277
B	ARG278
B	HOH1232
B	HOH1565

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA B 327

Chain	Residue
B	ASP259
B	HOH893
B	HOH1580
B	HOH2129
D	ASP259

site_id	AC7
Number of Residues	13
Details	BINDING SITE FOR RESIDUE 13P C 3003

Chain	Residue
C	ASP27
C	GLN28
C	LYS125
C	GLU163
C	LYS205
C	LEU248
C	SER249
C	ALA250
C	LEU275
C	GLY277
C	ARG278
C	HOH738
C	HOH1926

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA C 327

Chain	Residue
A	GLU83
A	GLU84
C	GLU238
C	THR241
C	HOH1277

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA C 328

Chain	Residue
C	ALA37
C	GLN40
C	HOH495
C	HOH779
C	HOH1812

site_id	BC1
Number of Residues	14
Details	BINDING SITE FOR RESIDUE 13P D 3004

Chain	Residue
D	ALA25
D	ASP27
D	GLN28
D	LEU68
D	LYS125
D	GLU163
D	LYS205
D	SER249
D	ALA250
D	LEU275
D	GLY277
D	ARG278
D	HOH924
D	HOH2410

site_id	BC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA D 327

Chain	Residue
D	GLU84
D	HOH959
D	HOH1282
D	HOH1820
D	HOH2164
D	HOH2165

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)