3LE7
Crystal structure of PD-L1 from P. dioica in complex with adenine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006952 | biological_process | defense response |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0017148 | biological_process | negative regulation of translation |
| A | 0030598 | molecular_function | rRNA N-glycosylase activity |
| A | 0035821 | biological_process | modulation of process of another organism |
| A | 0090729 | molecular_function | toxin activity |
| B | 0006952 | biological_process | defense response |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0017148 | biological_process | negative regulation of translation |
| B | 0030598 | molecular_function | rRNA N-glycosylase activity |
| B | 0035821 | biological_process | modulation of process of another organism |
| B | 0090729 | molecular_function | toxin activity |
Functional Information from PROSITE/UniProt
| site_id | PS00275 |
| Number of Residues | 17 |
| Details | SHIGA_RICIN Shiga/ricin ribosomal inactivating toxins active site signature. IqMVsEAARFKyIEnqV |
| Chain | Residue | Details |
| A | ILE173-VAL189 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | ACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:P84531 |
| Chain | Residue | Details |
| A | TYR75 | |
| A | TYR125 | |
| A | GLU178 | |
| A | ARG181 | |
| B | TYR75 | |
| B | TYR125 | |
| B | GLU178 | |
| B | ARG181 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:20174685, ECO:0007744|PDB:3LE7 |
| Chain | Residue | Details |
| A | VAL76 | |
| A | SER123 | |
| A | ARG181 | |
| B | VAL76 | |
| B | SER123 | |
| B | ARG181 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; in PD-L1 and PD-L2 => ECO:0000255|PROSITE-ProRule:PRU00498, ECO:0000269|PubMed:19014994, ECO:0000269|PubMed:19452522, ECO:0000269|PubMed:20174685, ECO:0007744|PDB:3H5K, ECO:0007744|PDB:3LE7 |
| Chain | Residue | Details |
| A | ASN13 | |
| B | ASN13 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; in PD-L1 and PD-L2 => ECO:0000255|PROSITE-ProRule:PRU00498, ECO:0000269|PubMed:10213004, ECO:0000269|PubMed:19014994 |
| Chain | Residue | Details |
| A | ASN46 | |
| B | ASN46 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; in PD-L1 => ECO:0000255|PROSITE-ProRule:PRU00498, ECO:0000269|PubMed:19014994 |
| Chain | Residue | Details |
| A | ASN258 | |
| B | ASN258 |
