3K6M

Dynamic domains of Succinyl-CoA:3-ketoacid-coenzyme A transferase from pig heart.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005739	cellular_component	mitochondrion
A	0006629	biological_process	lipid metabolic process
A	0008260	molecular_function	succinyl-CoA:3-oxo-acid CoA-transferase activity
A	0008410	molecular_function	CoA-transferase activity
A	0016740	molecular_function	transferase activity
A	0042803	molecular_function	protein homodimerization activity
A	0046950	biological_process	cellular ketone body metabolic process
A	0046952	biological_process	ketone body catabolic process
B	0005739	cellular_component	mitochondrion
B	0006629	biological_process	lipid metabolic process
B	0008260	molecular_function	succinyl-CoA:3-oxo-acid CoA-transferase activity
B	0008410	molecular_function	CoA-transferase activity
B	0016740	molecular_function	transferase activity
B	0042803	molecular_function	protein homodimerization activity
B	0046950	biological_process	cellular ketone body metabolic process
B	0046952	biological_process	ketone body catabolic process
C	0005739	cellular_component	mitochondrion
C	0006629	biological_process	lipid metabolic process
C	0008260	molecular_function	succinyl-CoA:3-oxo-acid CoA-transferase activity
C	0008410	molecular_function	CoA-transferase activity
C	0016740	molecular_function	transferase activity
C	0042803	molecular_function	protein homodimerization activity
C	0046950	biological_process	cellular ketone body metabolic process
C	0046952	biological_process	ketone body catabolic process
D	0005739	cellular_component	mitochondrion
D	0006629	biological_process	lipid metabolic process
D	0008260	molecular_function	succinyl-CoA:3-oxo-acid CoA-transferase activity
D	0008410	molecular_function	CoA-transferase activity
D	0016740	molecular_function	transferase activity
D	0042803	molecular_function	protein homodimerization activity
D	0046950	biological_process	cellular ketone body metabolic process
D	0046952	biological_process	ketone body catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 6000

Chain	Residue
A	ASN51
A	ASN52
A	TYR76
A	GLN99
A	LYS329

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CL D 6001

Chain	Residue
D	GLN99
D	LYS329
D	PHE25
D	ASN51
D	ASN52
D	TYR76

---

site_id	AC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GOL C 5000

Chain	Residue
C	PHE25
C	ASN51
C	ASN52
C	GLN99
C	ILE284
C	GLU305
C	ALA327
C	GLY385
C	HOH5257
C	HOH5334

---

site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL C 5001

Chain	Residue
C	VAL391
C	SER393
C	ALA394
C	THR396
C	VAL398
C	CYS426
C	ASN428
C	HOH5490

---

Functional Information from PROSITE/UniProt

site_id	PS01273
Number of Residues	16
Details	COA_TRANSF_1 Coenzyme A transferases signature 1. NGatVLVGGFglcGiP

Chain	Residue	Details
A	ASN16-PRO31

---

site_id	PS01274
Number of Residues	9
Details	COA_TRANSF_2 Coenzyme A transferases signature 2. LQSENGILG

Chain	Residue	Details
A	LEU302-GLY310

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: 5-glutamyl coenzyme A thioester intermediate => ECO:0000255|PROSITE-ProRule:PRU10034, ECO:0000269|PubMed:7915164

Chain	Residue	Details
A	GLU305
D	GLU305
C	GLU305
B	GLU305

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P55809

Chain	Residue	Details
A	SER131
D	SER131
C	SER131
B	SER131

---

site_id	SWS_FT_FI3
Number of Residues	16
Details	MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:Q9D0K2

Chain	Residue	Details
A	LYS146
C	LYS379
C	LYS382
C	LYS416
B	LYS146
B	LYS379
B	LYS382
B	LYS416
A	LYS379
A	LYS382
A	LYS416
D	LYS146
D	LYS379
D	LYS382
D	LYS416
C	LYS146

---