Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0016020 | cellular_component | membrane |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0016020 | cellular_component | membrane |
| C | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
| C | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE AYH A 387 |
| Chain | Residue |
| A | GLN12 |
| A | ILE126 |
| A | TYR198 |
| A | ASP228 |
| A | GLY230 |
| A | THR231 |
| A | THR232 |
| A | HOH419 |
| A | GLY13 |
| A | ASP32 |
| A | GLY34 |
| A | PRO70 |
| A | TYR71 |
| A | THR72 |
| A | GLN73 |
| A | PHE108 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE AYH B 387 |
| Chain | Residue |
| B | GLN12 |
| B | GLY13 |
| B | ASP32 |
| B | GLY34 |
| B | PRO70 |
| B | TYR71 |
| B | THR72 |
| B | GLN73 |
| B | PHE108 |
| B | ILE126 |
| B | TYR198 |
| B | ASP228 |
| B | GLY230 |
| B | THR232 |
| B | HOH477 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE AYH C 387 |
| Chain | Residue |
| C | GLN12 |
| C | GLY13 |
| C | ASP32 |
| C | GLY34 |
| C | PRO70 |
| C | TYR71 |
| C | THR72 |
| C | GLN73 |
| C | PHE108 |
| C | ILE126 |
| C | TYR198 |
| C | ASP228 |
| C | GLY230 |
| C | THR231 |
| C | THR232 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ILVDTGSSNFAV |
| Chain | Residue | Details |
| A | ILE29-VAL40 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | LEU80 | |
| A | PRO276 | |
| B | LEU80 | |
| B | PRO276 | |
| C | LEU80 | |
| C | PRO276 | |
| Chain | Residue | Details |
| A | SER113 | |
| A | TRP262 | |
| A | GLN266 | |
| A | ALA272 | |
| A | TYR286 | |
| A | LEU287 | |
| A | GLN294 | |
| B | SER113 | |
| B | TRP262 | |
| B | GLN266 | |
| B | ALA272 | |
| B | TYR286 | |
| B | LEU287 | |
| B | GLN294 | |
| C | SER113 | |
| C | TRP262 | |
| C | GLN266 | |
| C | ALA272 | |
| C | TYR286 | |
| C | LEU287 | |
| C | GLN294 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | LEU140 | |
| A | PHE159 | |
| A | GLY210 | |
| A | PHE341 | |
| B | LEU140 | |
| B | PHE159 | |
| B | GLY210 | |
| B | PHE341 | |
| C | LEU140 | |
| C | PHE159 | |
| C | GLY210 | |
| C | PHE341 | |
