Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003848 | molecular_function | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0009396 | biological_process | folic acid-containing compound biosynthetic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
| A | 0046656 | biological_process | folic acid biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 161 |
| Chain | Residue |
| A | ASP97 |
| A | APC171 |
| A | HOH201 |
| A | HOH202 |
| A | HOH203 |
| site_id | AC2 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE APC A 171 |
| Chain | Residue |
| A | PRO91 |
| A | ARG92 |
| A | ASP97 |
| A | ILE98 |
| A | ARG110 |
| A | LEU111 |
| A | THR112 |
| A | HIS115 |
| A | TYR116 |
| A | ARG121 |
| A | HIS148 |
| A | MG161 |
| A | HOH201 |
| A | HOH202 |
| A | HOH203 |
| A | HOH205 |
| A | HOH257 |
| A | HOH280 |
| A | HOH334 |
| A | HOH339 |
| A | HOH362 |
| A | HOH365 |
| A | LYS23 |
| A | ASP27 |
| A | GLN74 |
| A | ARG88 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 191 |
| Chain | Residue |
| A | LEU100 |
| A | PHE101 |
| A | GLY102 |
| A | GLU104 |
| A | VAL113 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT A 192 |
| Chain | Residue |
| A | THR42 |
| A | TYR53 |
| A | ASN55 |
| A | PHE123 |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 151 |
| Chain | Residue | Details |
| A | ARG82 | electrostatic stabiliser, hydrogen bond donor |
| A | ARG92 | electrostatic stabiliser, hydrogen bond donor |
| A | ALA95 | metal ligand |
| A | ASP97 | metal ligand |
