3HLV
Crystal structure of human Estrogen Receptor Alpha Ligand-Binding Domain in complex with a Glucocorticoid Receptor Interacting Protein 1 Nr Box II Peptide and 16-alpha-hydroxy-estrone ((8S,9R,13S,14R,16R)-3,16-dihydroxy-13-methyl-7,8,9,11,12,14,15, 16-octahydro-6H-cyclopenta[a]phenanthren-17-one
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE J2Z A 1 |
| Chain | Residue |
| A | MET343 |
| A | LEU525 |
| A | LEU346 |
| A | LEU349 |
| A | GLU353 |
| A | LEU387 |
| A | LEU391 |
| A | ARG394 |
| A | ILE424 |
| A | GLY521 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE J2Z B 2 |
| Chain | Residue |
| B | MET343 |
| B | GLU353 |
| B | LEU391 |
| B | ARG394 |
| B | MET421 |
| B | GLY521 |
| B | HIS524 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | SER537 | |
| B | SER537 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | LIPID: S-palmitoyl cysteine => ECO:0000250 |
| Chain | Residue | Details |
| A | CYS447 | |
| B | CYS447 | |
