3HBG

Structure of recombinant Chicken Liver Sulfite Oxidase mutant C185S

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005739	cellular_component	mitochondrion
A	0005758	cellular_component	mitochondrial intermembrane space
A	0006790	biological_process	sulfur compound metabolic process
A	0008482	molecular_function	sulfite oxidase activity
A	0016491	molecular_function	oxidoreductase activity
A	0020037	molecular_function	heme binding
A	0030151	molecular_function	molybdenum ion binding
A	0043546	molecular_function	molybdopterin cofactor binding
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	BINDING SITE FOR RESIDUE MTE A 501

Chain	Residue
A	PHE135
A	GLY296
A	ALA297
A	SER299
A	VAL300
A	LYS301
A	TRP302
A	MOM502
A	PHE136
A	THR137
A	ARG138
A	HIS140
A	ASP244
A	TYR252
A	HIS283
A	ARG288

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MOM A 502

Chain	Residue
A	ARG138
A	SER185
A	ALA186
A	VAL295
A	ALA297
A	MTE501

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Functional Information from PROSITE/UniProt

site_id	PS00191
Number of Residues	8
Details	CYTOCHROME_B5_1 Cytochrome b5 family, heme-binding domain signature. FVELHPGG

Chain	Residue	Details
A	PHE36-GLY43

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING: axial binding residue => ECO:0000269|PubMed:9428520

Chain	Residue	Details
A	HIS40
A	HIS65

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site_id	SWS_FT_FI2
Number of Residues	7
Details	BINDING: BINDING => ECO:0000269|PubMed:9428520

Chain	Residue	Details
A	HIS69
A	PHE136
A	SER185
A	ASP244
A	HIS283
A	ARG288
A	SER299

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues	5
Details	M-CSA 121

Chain	Residue	Details
A	HIS40	metal ligand
A	HIS65	metal ligand
A	ARG138	steric role
A	SER185	metal ligand
A	TYR322	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay

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