3GZX
Crystal Structure of the Biphenyl Dioxygenase in complex with Biphenyl from Comamonas testosteroni Sp. Strain B-356
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0018687 | molecular_function | biphenyl 2,3-dioxygenase activity |
| A | 0019439 | biological_process | obsolete aromatic compound catabolic process |
| A | 0044237 | biological_process | cellular metabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051213 | molecular_function | dioxygenase activity |
| A | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
| B | 0006725 | biological_process | obsolete cellular aromatic compound metabolic process |
| B | 0018687 | molecular_function | biphenyl 2,3-dioxygenase activity |
| B | 0019380 | biological_process | 3-phenylpropionate catabolic process |
| B | 0019439 | biological_process | obsolete aromatic compound catabolic process |
| B | 0051213 | molecular_function | dioxygenase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FE2 A 701 |
| Chain | Residue |
| A | GLN226 |
| A | HIS233 |
| A | HIS239 |
| A | ASP386 |
| A | HOH458 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FES A 700 |
| Chain | Residue |
| A | HIS123 |
| A | TRP125 |
| A | CYS100 |
| A | HIS102 |
| A | ARG103 |
| A | CYS120 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE BNL A 702 |
| Chain | Residue |
| A | GLN226 |
| A | PHE227 |
| A | ASP230 |
| A | HIS233 |
| A | GLY319 |
| A | HIS321 |
| A | LEU331 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 705 |
| Chain | Residue |
| A | LEU74 |
| A | ASP111 |
| A | GLY112 |
| A | HOH661 |
| A | GOL706 |
| A | HOH737 |
| A | HOH756 |
| B | ARG62 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 706 |
| Chain | Residue |
| A | HIS66 |
| A | PRO68 |
| A | LYS69 |
| A | ASP72 |
| A | GOL705 |
| A | HOH818 |
| site_id | AC6 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE MES B 704 |
| Chain | Residue |
| A | ASN279 |
| A | ASN279 |
| A | HOH819 |
| B | ARG118 |
| B | ARG118 |
| B | MET120 |
| B | ASP121 |
| B | ASP121 |
| B | HOH515 |
| B | HOH617 |
| B | HOH617 |
Functional Information from PROSITE/UniProt
| site_id | PS00570 |
| Number of Residues | 24 |
| Details | RING_HYDROXYL_ALPHA Bacterial ring hydroxylating dioxygenases alpha-subunit signature. CrHRGmrivrsdgGNakaftCtYH |
| Chain | Residue | Details |
| A | CYS100-HIS123 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00628 |
| Chain | Residue | Details |
| A | CYS100 | |
| A | CYS120 | |
| A | HIS123 | |
| A | HIS102 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | HIS233 | |
| A | HIS239 |
