3GIQ
Crystal structure of N-acyl-D-Glutamate Deacylase from Bordetella Bronchiseptica complexed with zinc and phosphonate inhibitor, a mimic of the reaction tetrahedral intermediate.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| A | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0047421 | molecular_function | N-acyl-D-glutamate deacylase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| B | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0047421 | molecular_function | N-acyl-D-glutamate deacylase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE G01 A 481 |
| Chain | Residue |
| A | HIS66 |
| A | TYR282 |
| A | SER287 |
| A | SER288 |
| A | ARG295 |
| A | ASP365 |
| A | ARG376 |
| A | ZN482 |
| A | ZN483 |
| A | HOH522 |
| A | HIS68 |
| A | CYS95 |
| A | TYR190 |
| A | HIS218 |
| A | GLU222 |
| A | HIS248 |
| A | LYS250 |
| A | MET252 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 482 |
| Chain | Residue |
| A | CYS95 |
| A | HIS218 |
| A | HIS248 |
| A | G01481 |
| A | ZN483 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN A 483 |
| Chain | Residue |
| A | HIS66 |
| A | HIS68 |
| A | CYS95 |
| A | ASP365 |
| A | G01481 |
| A | ZN482 |
| site_id | AC4 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE G01 B 481 |
| Chain | Residue |
| B | HIS66 |
| B | HIS68 |
| B | CYS95 |
| B | TYR190 |
| B | HIS218 |
| B | GLU222 |
| B | HIS248 |
| B | LYS250 |
| B | MET252 |
| B | TYR282 |
| B | SER287 |
| B | SER288 |
| B | ARG295 |
| B | ASP365 |
| B | ARG376 |
| B | ZN482 |
| B | ZN483 |
| B | HOH495 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 482 |
| Chain | Residue |
| B | CYS95 |
| B | HIS218 |
| B | HIS248 |
| B | G01481 |
| B | ZN483 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN B 483 |
| Chain | Residue |
| B | HIS66 |
| B | HIS68 |
| B | CYS95 |
| B | ASP365 |
| B | G01481 |
| B | ZN482 |
