Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004590 | molecular_function | orotidine-5'-phosphate decarboxylase activity |
| A | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| A | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
| B | 0004590 | molecular_function | orotidine-5'-phosphate decarboxylase activity |
| B | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| B | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE 5FU A3000 |
| Chain | Residue |
| A | SER68 |
| A | GLN241 |
| A | TYR243 |
| A | GLY261 |
| A | ARG262 |
| A | HOH295 |
| A | HOH297 |
| A | HOH298 |
| A | HOH330 |
| B | ASP128 |
| B | ILE129 |
| A | ASP70 |
| B | THR132 |
| A | LYS92 |
| A | HIS94 |
| A | ASP123 |
| A | LYS125 |
| A | MET182 |
| A | SER183 |
| A | PRO228 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE 5FU B3000 |
| Chain | Residue |
| A | ASP128 |
| A | ILE129 |
| A | THR132 |
| B | SER68 |
| B | ASP70 |
| B | LYS92 |
| B | HIS94 |
| B | ASP123 |
| B | LYS125 |
| B | MET182 |
| B | SER183 |
| B | PRO228 |
| B | GLN241 |
| B | TYR243 |
| B | GLY261 |
| B | ARG262 |
| B | HOH300 |
| B | HOH338 |
| B | HOH345 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A1000 |
| Chain | Residue |
| A | LYS53 |
| A | ALA113 |
| A | LYS114 |
| A | PHE118 |
| A | LEU119 |
| A | ASP149 |
| A | HOH390 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL B1001 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B1002 |
| Chain | Residue |
| B | ASP269 |
| B | GLU272 |
| B | MET276 |
| B | HOH348 |
| B | HOH425 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B2000 |
| Chain | Residue |
| B | GLY39 |
| B | ALA40 |
| B | GLU43 |
| B | HOH359 |
Functional Information from PROSITE/UniProt
| site_id | PS00156 |
| Number of Residues | 14 |
| Details | OMPDECASE Orotidine 5'-phosphate decarboxylase active site. IFeDrKfaDIGnTV |
| Chain | Residue | Details |
| A | ILE120-VAL133 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP123 | |
| A | LYS125 | |
| A | ASP128 | |
| B | ASP123 | |
| B | LYS125 | |
| B | ASP128 | |
| Chain | Residue | Details |
| A | THR132 | |
| B | SER68 | |
| B | ASP128 | |
| B | THR132 | |
| A | SER68 | |
| A | ASP128 | |
| Chain | Residue | Details |
| A | ASP70 | |
| A | SER183 | |
| B | ASP70 | |
| B | SER183 | |
| B | GLN241 | |
| B | GLY261 | |
| A | GLN241 | |
| A | GLY261 | |
| Chain | Residue | Details |
| A | LYS92 | |
| A | LYS125 | |
| B | LYS92 | |
| B | LYS125 | |
| Chain | Residue | Details |
| A | SER25 | |
| B | SER25 | |
