3FGH
Human mitochondrial transcription factor A box B
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD A 1 |
| Chain | Residue |
| A | HOH46 |
| A | GLU166 |
| A | HIS170 |
| A | CL178 |
| A | CL179 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD A 2 |
| Chain | Residue |
| A | HOH28 |
| A | HOH34 |
| A | ASP152 |
| A | GLU164 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 178 |
| Chain | Residue |
| A | CD1 |
| A | HOH46 |
| A | ALA119 |
| A | GLU166 |
| A | HIS170 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL A 179 |
| Chain | Residue |
| A | CD1 |
| A | HOH46 |
| A | ARG115 |
| A | GLU166 |
| A | GLU166 |
| A | TYR169 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NA A 180 |
| Chain | Residue |
| A | HOH52 |
| A | HOH53 |
| A | ASP165 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NA A 181 |
| Chain | Residue |
| A | SER151 |
| A | SER153 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 64 |
| Details | DNA_BIND: HMG box 2 => ECO:0000255|PROSITE-ProRule:PRU00267 |
| Chain | Residue | Details |
| A | PRO113-ALA177 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | SITE: Intercalates between bases and promotes DNA bending |
| Chain | Residue | Details |
| A | LEU140 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; by PKA => ECO:0000269|PubMed:23201127 |
| Chain | Residue | Details |
| A | SER118 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER151 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER153 |
