3EMB
Wesselsbron virus Methyltransferase in complex with AdoMet and 7MeGpppG
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004482 | molecular_function | mRNA 5'-cap (guanine-N7-)-methyltransferase activity |
| A | 0004483 | molecular_function | mRNA (nucleoside-2'-O-)-methyltransferase activity |
| A | 0006370 | biological_process | 7-methylguanosine mRNA capping |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0032259 | biological_process | methylation |
| A | 0106005 | biological_process | RNA 5'-cap (guanine-N7)-methylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE SAM A4633 |
| Chain | Residue |
| A | SER56 |
| A | GLU111 |
| A | SER130 |
| A | ASN131 |
| A | VAL132 |
| A | PHE133 |
| A | ASP146 |
| A | HOH4646 |
| A | HOH4651 |
| A | HOH4680 |
| A | GLY58 |
| A | GLY81 |
| A | CYS82 |
| A | GLY83 |
| A | GLY86 |
| A | TRP87 |
| A | THR104 |
| A | LEU105 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE GTG A4634 |
| Chain | Residue |
| A | LYS13 |
| A | LEU16 |
| A | ASN17 |
| A | LEU19 |
| A | PHE24 |
| A | ARG57 |
| A | SER150 |
| A | SER151 |
| A | SER152 |
| A | GLU193 |
| A | ARG197 |
| A | SER215 |
| A | SO44636 |
| A | HOH4766 |
| A | HOH4776 |
| A | HOH4809 |
| A | HOH4810 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A4635 |
| Chain | Residue |
| A | ARG37 |
| A | ARG41 |
| A | ARG57 |
| A | ARG84 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A4636 |
| Chain | Residue |
| A | GLY58 |
| A | LYS61 |
| A | GTG4634 |
| A | HOH4824 |
