Functional Information from GO Data
| Chain | GOid | namespace | contents |
| E | 0004175 | molecular_function | endopeptidase activity |
| E | 0004252 | molecular_function | serine-type endopeptidase activity |
| E | 0005515 | molecular_function | protein binding |
| E | 0005576 | cellular_component | extracellular region |
| E | 0005615 | cellular_component | extracellular space |
| E | 0006508 | biological_process | proteolysis |
| E | 0007586 | biological_process | digestion |
| E | 0008233 | molecular_function | peptidase activity |
| E | 0008236 | molecular_function | serine-type peptidase activity |
| E | 0016787 | molecular_function | hydrolase activity |
| E | 0046872 | molecular_function | metal ion binding |
| E | 0097180 | cellular_component | serine protease inhibitor complex |
| E | 0097655 | molecular_function | serpin family protein binding |
| I | 0004867 | molecular_function | serine-type endopeptidase inhibitor activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA E 600 |
| Chain | Residue |
| E | GLU70 |
| E | ASN72 |
| E | VAL75 |
| E | GLU80 |
| E | HOH722 |
| E | HOH745 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 I 601 |
| Chain | Residue |
| I | ARG542 |
| I | HOH775 |
| I | HOH806 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 I 602 |
| Chain | Residue |
| E | HOH865 |
| I | ARG520 |
| I | TYR535 |
| I | ALA540 |
| I | HOH799 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 E 603 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 I 604 |
| Chain | Residue |
| E | SER86 |
| E | LYS87 |
| E | LYS107 |
| I | ARG542 |
| I | HOH801 |
Functional Information from PROSITE/UniProt
| site_id | PS00280 |
| Number of Residues | 19 |
| Details | BPTI_KUNITZ_1 Pancreatic trypsin inhibitor (Kunitz) family signature. FvyGGCrakrnnFksaedC |
| Chain | Residue | Details |
| I | PHE533-CYS551 | |
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| E | VAL53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPVV |
| Chain | Residue | Details |
| E | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | SITE: Reactive bond for trypsin |
| Chain | Residue | Details |
| I | ASP550 | |
| E | LEU105 | |
| E | PRO198 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | BINDING: |
| Chain | Residue | Details |
| E | ILE73 | |
| E | VAL75 | |
| E | GLY78 | |
| E | ILE83 | |
| E | GLN192 | |
| E | SER195 | |
| E | PRO198 | |
