Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3AQ0

Ligand-bound form of Arabidopsis medium/long-chain length prenyl pyrophosphate synthase (surface polar residue mutant)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008299	biological_process	isoprenoid biosynthetic process
B	0008299	biological_process	isoprenoid biosynthetic process
C	0008299	biological_process	isoprenoid biosynthetic process
D	0008299	biological_process	isoprenoid biosynthetic process
E	0008299	biological_process	isoprenoid biosynthetic process
F	0008299	biological_process	isoprenoid biosynthetic process
G	0008299	biological_process	isoprenoid biosynthetic process
H	0008299	biological_process	isoprenoid biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG A 1000

Chain	Residue
A	ASP107
A	ASP111
A	FPP1002

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 1001

Chain	Residue
A	ASP107
A	ASP111
A	GLU169
A	GLU172
A	FPP1002

site_id	AC3
Number of Residues	12
Details	BINDING SITE FOR RESIDUE FPP A 1002

Chain	Residue
A	SER103
A	HIS106
A	ASP107
A	ASP111
A	ARG116
A	GLU169
A	LYS193
A	HOH439
A	MG1000
A	MG1001
B	ASP136
A	ALA102

site_id	AC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE ISY A 1003

Chain	Residue
A	GLY50
A	LYS51
A	PHE53
A	ARG54
A	HIS100
A	ARG117
A	THR194
A	ILE198
A	HOH638

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PPV B 1000

Chain	Residue
B	GLN49
B	GLY50
B	LYS51
B	ARG54
B	HIS100
B	HOH659

site_id	AC6
Number of Residues	13
Details	BINDING SITE FOR RESIDUE FPP B 1001

Chain	Residue
B	PHE53
B	ILE57
B	ILE198
B	GLY227
B	PHE230
B	LEU339
B	ARG342
B	VAL343
B	ARG346
B	ASN347
B	LYS348
F	PHE11
F	HIS341

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PEG B 1002

Chain	Residue
B	GLU32
B	LYS35
B	HOH616
E	THR170
F	PHE137

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C 1000

Chain	Residue
C	ASP107
C	ASP111
C	GLU169
C	GLU172
C	FPP1002

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C 1001

Chain	Residue
C	ASP107
C	ASP108
C	ASP111
C	ARG116
C	FPP1002

site_id	BC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE FPP C 1002

Chain	Residue
C	ILE99
C	SER103
C	HIS106
C	ASP107
C	ASP111
C	ARG116
C	GLU169
C	LYS193
C	MG1000
C	MG1001
D	ASP136

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PPV C 1003

Chain	Residue
C	LYS51
C	ARG54
C	HIS100
C	ARG117
C	HOH426

site_id	BC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PPV D 1000

Chain	Residue
D	ARG54
D	GLU97
D	HIS100
D	LEU104
D	HOH373

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PEG D 1002

Chain	Residue
C	THR170
D	PHE137
D	ARG141
D	HOH611
G	GLU32

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG E 1000

Chain	Residue
E	ASP107
E	ASP111
E	GLU172
E	FPP1002

site_id	BC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG E 1001

Chain	Residue
E	ASP107
E	ASP111
E	FPP1002

site_id	BC7
Number of Residues	11
Details	BINDING SITE FOR RESIDUE FPP E 1002

Chain	Residue
E	ASP111
E	ARG116
E	GLU169
E	LYS193
E	HOH559
E	MG1000
E	MG1001
F	ASP136
E	SER103
E	HIS106
E	ASP107

site_id	BC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PPV E 1003

Chain	Residue
E	LYS51
E	ARG54
E	HIS100
E	ARG117
E	HOH428
E	HOH557

site_id	BC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PPV F 1000

Chain	Residue
F	ARG54
F	HIS100
F	HOH620

site_id	CC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PPV G 1000

Chain	Residue
G	GLN49
G	LYS51
G	ARG54
G	HIS100

site_id	CC2
Number of Residues	13
Details	BINDING SITE FOR RESIDUE FPP G 1001

Chain	Residue
D	PHE11
D	HIS341
G	PHE53
G	ILE57
G	PHE230
G	LEU339
G	VAL343
G	ARG346
G	ASN347
G	LYS348
G	HOH367
G	HOH368
G	HOH674

site_id	CC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG H 1000

Chain	Residue
H	ASP107
H	ASP111
H	GLU169
H	FPP1002

site_id	CC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG H 1001

Chain	Residue
H	ASP107
H	ASP111
H	FPP1002

site_id	CC5
Number of Residues	10
Details	BINDING SITE FOR RESIDUE FPP H 1002

Chain	Residue
G	ASP136
H	ALA102
H	SER103
H	ASP107
H	ASP111
H	ARG116
H	GLU169
H	LYS193
H	MG1000
H	MG1001

site_id	CC6
Number of Residues	11
Details	BINDING SITE FOR RESIDUE ISY H 1003

Chain	Residue
H	GLY50
H	LYS51
H	PHE53
H	ARG54
H	HIS100
H	ARG117
H	THR194
H	ILE198
H	HOH353
H	HOH377
H	HOH386

Functional Information from PROSITE/UniProt

site_id	PS00444
Number of Residues	13
Details	POLYPRENYL_SYNTHASE_2 Polyprenyl synthases signature 2. LGlaFQLiDDIlD

Chain	Residue	Details
A	LEU226-ASP238

site_id	PS00723
Number of Residues	15
Details	POLYPRENYL_SYNTHASE_1 Polyprenyl synthases signature 1. LLhDDvl..DdadtRRG

Chain	Residue	Details
A	LEU104-GLY118

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	40
Details	BINDING: BINDING => ECO:0000250\|UniProtKB:P14324

Chain	Residue	Details
D	ARG54
D	ASP107
D	ASP111
D	ARG117
E	LYS51
E	ARG54
E	ASP107
E	ASP111
E	ARG117
F	LYS51
F	ARG54
F	ASP107
F	ASP111
F	ARG117
G	LYS51
G	ARG54
G	ASP107
G	ASP111
G	ARG117
H	LYS51
H	ARG54
H	ASP107
H	ASP111
H	ARG117
A	LYS51
A	ARG54
A	ASP107
A	ASP111
A	ARG117
B	LYS51
B	ARG54
B	ASP107
B	ASP111
B	ARG117
C	LYS51
C	ARG54
C	ASP107
C	ASP111
C	ARG117
D	LYS51

site_id	SWS_FT_FI2
Number of Residues	8
Details	BINDING: BINDING => ECO:0000250\|UniProtKB:Q12051

Chain	Residue	Details
A	HIS100
B	HIS100
C	HIS100
D	HIS100
E	HIS100
F	HIS100
G	HIS100
H	HIS100

site_id	SWS_FT_FI3
Number of Residues	40
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
B	GLN231
B	LYS248
C	ARG116
C	LYS193
C	THR194
C	GLN231
C	LYS248
D	ARG116
D	LYS193
D	THR194
D	GLN231
D	LYS248
E	ARG116
E	LYS193
E	THR194
E	GLN231
E	LYS248
F	ARG116
F	LYS193
F	THR194
F	GLN231
F	LYS248
G	ARG116
G	LYS193
G	THR194
G	GLN231
G	LYS248
H	ARG116
H	LYS193
H	THR194
H	GLN231
H	LYS248
A	ARG116
A	LYS193
A	THR194
A	GLN231
A	LYS248
B	ARG116
B	LYS193
B	THR194

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)