Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3A59

Structure of Hemoglobin from flightless bird (Struthio camelus)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004601	molecular_function	peroxidase activity
A	0005344	molecular_function	oxygen carrier activity
A	0005506	molecular_function	iron ion binding
A	0005833	cellular_component	hemoglobin complex
A	0015671	biological_process	oxygen transport
A	0019825	molecular_function	oxygen binding
A	0020037	molecular_function	heme binding
A	0031720	molecular_function	haptoglobin binding
A	0031838	cellular_component	haptoglobin-hemoglobin complex
A	0042744	biological_process	hydrogen peroxide catabolic process
A	0043177	molecular_function	organic acid binding
A	0046872	molecular_function	metal ion binding
A	0072562	cellular_component	blood microparticle
A	0098869	biological_process	cellular oxidant detoxification
B	0004601	molecular_function	peroxidase activity
B	0005344	molecular_function	oxygen carrier activity
B	0005833	cellular_component	hemoglobin complex
B	0015671	biological_process	oxygen transport
B	0019825	molecular_function	oxygen binding
B	0020037	molecular_function	heme binding
B	0031720	molecular_function	haptoglobin binding
B	0031721	molecular_function	hemoglobin alpha binding
B	0031838	cellular_component	haptoglobin-hemoglobin complex
B	0042744	biological_process	hydrogen peroxide catabolic process
B	0043177	molecular_function	organic acid binding
B	0046872	molecular_function	metal ion binding
B	0072562	cellular_component	blood microparticle
B	0098869	biological_process	cellular oxidant detoxification
C	0004601	molecular_function	peroxidase activity
C	0005344	molecular_function	oxygen carrier activity
C	0005506	molecular_function	iron ion binding
C	0005833	cellular_component	hemoglobin complex
C	0015671	biological_process	oxygen transport
C	0019825	molecular_function	oxygen binding
C	0020037	molecular_function	heme binding
C	0031720	molecular_function	haptoglobin binding
C	0031838	cellular_component	haptoglobin-hemoglobin complex
C	0042744	biological_process	hydrogen peroxide catabolic process
C	0043177	molecular_function	organic acid binding
C	0046872	molecular_function	metal ion binding
C	0072562	cellular_component	blood microparticle
C	0098869	biological_process	cellular oxidant detoxification
D	0004601	molecular_function	peroxidase activity
D	0005344	molecular_function	oxygen carrier activity
D	0005833	cellular_component	hemoglobin complex
D	0015671	biological_process	oxygen transport
D	0019825	molecular_function	oxygen binding
D	0020037	molecular_function	heme binding
D	0031720	molecular_function	haptoglobin binding
D	0031721	molecular_function	hemoglobin alpha binding
D	0031838	cellular_component	haptoglobin-hemoglobin complex
D	0042744	biological_process	hydrogen peroxide catabolic process
D	0043177	molecular_function	organic acid binding
D	0046872	molecular_function	metal ion binding
D	0072562	cellular_component	blood microparticle
D	0098869	biological_process	cellular oxidant detoxification
E	0004601	molecular_function	peroxidase activity
E	0005344	molecular_function	oxygen carrier activity
E	0005506	molecular_function	iron ion binding
E	0005833	cellular_component	hemoglobin complex
E	0015671	biological_process	oxygen transport
E	0019825	molecular_function	oxygen binding
E	0020037	molecular_function	heme binding
E	0031720	molecular_function	haptoglobin binding
E	0031838	cellular_component	haptoglobin-hemoglobin complex
E	0042744	biological_process	hydrogen peroxide catabolic process
E	0043177	molecular_function	organic acid binding
E	0046872	molecular_function	metal ion binding
E	0072562	cellular_component	blood microparticle
E	0098869	biological_process	cellular oxidant detoxification
F	0004601	molecular_function	peroxidase activity
F	0005344	molecular_function	oxygen carrier activity
F	0005833	cellular_component	hemoglobin complex
F	0015671	biological_process	oxygen transport
F	0019825	molecular_function	oxygen binding
F	0020037	molecular_function	heme binding
F	0031720	molecular_function	haptoglobin binding
F	0031721	molecular_function	hemoglobin alpha binding
F	0031838	cellular_component	haptoglobin-hemoglobin complex
F	0042744	biological_process	hydrogen peroxide catabolic process
F	0043177	molecular_function	organic acid binding
F	0046872	molecular_function	metal ion binding
F	0072562	cellular_component	blood microparticle
F	0098869	biological_process	cellular oxidant detoxification
G	0004601	molecular_function	peroxidase activity
G	0005344	molecular_function	oxygen carrier activity
G	0005506	molecular_function	iron ion binding
G	0005833	cellular_component	hemoglobin complex
G	0015671	biological_process	oxygen transport
G	0019825	molecular_function	oxygen binding
G	0020037	molecular_function	heme binding
G	0031720	molecular_function	haptoglobin binding
G	0031838	cellular_component	haptoglobin-hemoglobin complex
G	0042744	biological_process	hydrogen peroxide catabolic process
G	0043177	molecular_function	organic acid binding
G	0046872	molecular_function	metal ion binding
G	0072562	cellular_component	blood microparticle
G	0098869	biological_process	cellular oxidant detoxification
H	0004601	molecular_function	peroxidase activity
H	0005344	molecular_function	oxygen carrier activity
H	0005833	cellular_component	hemoglobin complex
H	0015671	biological_process	oxygen transport
H	0019825	molecular_function	oxygen binding
H	0020037	molecular_function	heme binding
H	0031720	molecular_function	haptoglobin binding
H	0031721	molecular_function	hemoglobin alpha binding
H	0031838	cellular_component	haptoglobin-hemoglobin complex
H	0042744	biological_process	hydrogen peroxide catabolic process
H	0043177	molecular_function	organic acid binding
H	0046872	molecular_function	metal ion binding
H	0072562	cellular_component	blood microparticle
H	0098869	biological_process	cellular oxidant detoxification

Functional Information from PDB Data

site_id	AC1
Number of Residues	15
Details	BINDING SITE FOR RESIDUE HEM A 150

Chain	Residue
A	TYR42
A	VAL93
A	ASN97
A	PHE98
A	LEU101
A	VAL132
A	LEU136
A	PHE43
A	HIS45
A	HIS58
A	LYS61
A	VAL62
A	LEU86
A	HIS87
A	LEU91

site_id	AC2
Number of Residues	14
Details	BINDING SITE FOR RESIDUE HEM B 150

Chain	Residue
B	PHE41
B	PHE42
B	LYS66
B	PHE71
B	LEU88
B	LEU91
B	HIS92
B	LEU96
B	VAL98
B	ASN102
B	PHE103
B	LEU106
B	LEU141
H	LYS120

site_id	AC3
Number of Residues	16
Details	BINDING SITE FOR RESIDUE HEM C 150

Chain	Residue
C	TYR42
C	PHE43
C	HIS45
C	PHE46
C	HIS58
C	LYS61
C	VAL62
C	ALA65
C	LYS82
C	LEU83
C	HIS87
C	LEU91
C	VAL93
C	PHE98
C	LEU101
C	LEU136

site_id	AC4
Number of Residues	18
Details	BINDING SITE FOR RESIDUE HEM D 150

Chain	Residue
D	LEU31
D	PHE41
D	PHE42
D	SER44
D	HIS63
D	LYS66
D	VAL67
D	PHE71
D	PHE85
D	LEU88
D	HIS92
D	LEU96
D	VAL98
D	ASN102
D	PHE103
D	LEU106
D	LEU141
F	LYS120

site_id	AC5
Number of Residues	11
Details	BINDING SITE FOR RESIDUE HEM E 150

Chain	Residue
E	HIS45
E	PHE46
E	HIS58
E	LYS61
E	VAL62
E	ALA65
E	LEU83
E	HIS87
E	LEU91
E	VAL93
E	LEU136

site_id	AC6
Number of Residues	14
Details	BINDING SITE FOR RESIDUE HEM F 150

Chain	Residue
D	LYS120
F	PHE41
F	PHE42
F	HIS63
F	LYS66
F	VAL67
F	SER70
F	PHE71
F	HIS92
F	LEU96
F	ASN102
F	PHE103
F	LEU106
F	LEU141

site_id	AC7
Number of Residues	11
Details	BINDING SITE FOR RESIDUE HEM G 150

Chain	Residue
G	TYR42
G	PHE43
G	HIS45
G	HIS58
G	LYS61
G	VAL62
G	HIS87
G	LEU91
G	ASN97
G	PHE98
G	LEU136

site_id	AC8
Number of Residues	13
Details	BINDING SITE FOR RESIDUE HEM H 150

Chain	Residue
H	PHE41
H	PHE42
H	HIS63
H	LYS66
H	VAL67
H	PHE71
H	LEU91
H	HIS92
H	VAL98
H	ASN102
H	PHE103
H	LEU106
H	LEU141

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: distal binding residue

Chain	Residue	Details
B	HIS63
D	HIS63
F	HIS63
H	HIS63

site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: proximal binding residue

Chain	Residue	Details
B	HIS92
D	HIS92
F	HIS92
H	HIS92

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)