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3A58

Crystal structure of Sec3p - Rho1p complex from Saccharomyces cerevisiae

Functional Information from GO Data
ChainGOidnamespacecontents
B0000131cellular_componentincipient cellular bud site
B0000148cellular_component1,3-beta-D-glucan synthase complex
B0000329cellular_componentfungal-type vacuole membrane
B0003924molecular_functionGTPase activity
B0005515molecular_functionprotein binding
B0005525molecular_functionGTP binding
B0005739cellular_componentmitochondrion
B0005741cellular_componentmitochondrial outer membrane
B0005768cellular_componentendosome
B0005777cellular_componentperoxisome
B0005778cellular_componentperoxisomal membrane
B0005783cellular_componentendoplasmic reticulum
B0005794cellular_componentGolgi apparatus
B0005829cellular_componentcytosol
B0005886cellular_componentplasma membrane
B0005933cellular_componentcellular bud
B0005934cellular_componentcellular bud tip
B0005935cellular_componentcellular bud neck
B0006075biological_process(1->3)-beta-D-glucan biosynthetic process
B0007015biological_processactin filament organization
B0007117biological_processbudding cell bud growth
B0007165biological_processsignal transduction
B0007264biological_processsmall GTPase-mediated signal transduction
B0008047molecular_functionenzyme activator activity
B0008361biological_processregulation of cell size
B0009272biological_processfungal-type cell wall biogenesis
B0009277cellular_componentfungal-type cell wall
B0010008cellular_componentendosome membrane
B0016020cellular_componentmembrane
B0016787molecular_functionhydrolase activity
B0019901molecular_functionprotein kinase binding
B0030036biological_processactin cytoskeleton organization
B0030476biological_processascospore wall assembly
B0031160cellular_componentspore wall
B0031681molecular_functionG-protein beta-subunit binding
B0032186biological_processcellular bud neck septin ring organization
B0032880biological_processregulation of protein localization
B0032889biological_processregulation of vacuole fusion, non-autophagic
B0032956biological_processregulation of actin cytoskeleton organization
B0043332cellular_componentmating projection tip
B0045807biological_processpositive regulation of endocytosis
B0060178biological_processregulation of exocyst localization
B0060237biological_processregulation of fungal-type cell wall organization
B0071944cellular_componentcell periphery
B0090037biological_processpositive regulation of protein kinase C signaling
B0090334biological_processregulation of cell wall (1->3)-beta-D-glucan biosynthetic process
B1903395biological_processregulation of secondary cell septum biogenesis
B1903501biological_processpositive regulation of mitotic actomyosin contractile ring assembly
D0000131cellular_componentincipient cellular bud site
D0000148cellular_component1,3-beta-D-glucan synthase complex
D0000329cellular_componentfungal-type vacuole membrane
D0003924molecular_functionGTPase activity
D0005515molecular_functionprotein binding
D0005525molecular_functionGTP binding
D0005739cellular_componentmitochondrion
D0005741cellular_componentmitochondrial outer membrane
D0005768cellular_componentendosome
D0005777cellular_componentperoxisome
D0005778cellular_componentperoxisomal membrane
D0005783cellular_componentendoplasmic reticulum
D0005794cellular_componentGolgi apparatus
D0005829cellular_componentcytosol
D0005886cellular_componentplasma membrane
D0005933cellular_componentcellular bud
D0005934cellular_componentcellular bud tip
D0005935cellular_componentcellular bud neck
D0006075biological_process(1->3)-beta-D-glucan biosynthetic process
D0007015biological_processactin filament organization
D0007117biological_processbudding cell bud growth
D0007165biological_processsignal transduction
D0007264biological_processsmall GTPase-mediated signal transduction
D0008047molecular_functionenzyme activator activity
D0008361biological_processregulation of cell size
D0009272biological_processfungal-type cell wall biogenesis
D0009277cellular_componentfungal-type cell wall
D0010008cellular_componentendosome membrane
D0016020cellular_componentmembrane
D0016787molecular_functionhydrolase activity
D0019901molecular_functionprotein kinase binding
D0030036biological_processactin cytoskeleton organization
D0030476biological_processascospore wall assembly
D0031160cellular_componentspore wall
D0031681molecular_functionG-protein beta-subunit binding
D0032186biological_processcellular bud neck septin ring organization
D0032880biological_processregulation of protein localization
D0032889biological_processregulation of vacuole fusion, non-autophagic
D0032956biological_processregulation of actin cytoskeleton organization
D0043332cellular_componentmating projection tip
D0045807biological_processpositive regulation of endocytosis
D0060178biological_processregulation of exocyst localization
D0060237biological_processregulation of fungal-type cell wall organization
D0071944cellular_componentcell periphery
D0090037biological_processpositive regulation of protein kinase C signaling
D0090334biological_processregulation of cell wall (1->3)-beta-D-glucan biosynthetic process
D1903395biological_processregulation of secondary cell septum biogenesis
D1903501biological_processpositive regulation of mitotic actomyosin contractile ring assembly
F0000131cellular_componentincipient cellular bud site
F0000148cellular_component1,3-beta-D-glucan synthase complex
F0000329cellular_componentfungal-type vacuole membrane
F0003924molecular_functionGTPase activity
F0005515molecular_functionprotein binding
F0005525molecular_functionGTP binding
F0005739cellular_componentmitochondrion
F0005741cellular_componentmitochondrial outer membrane
F0005768cellular_componentendosome
F0005777cellular_componentperoxisome
F0005778cellular_componentperoxisomal membrane
F0005783cellular_componentendoplasmic reticulum
F0005794cellular_componentGolgi apparatus
F0005829cellular_componentcytosol
F0005886cellular_componentplasma membrane
F0005933cellular_componentcellular bud
F0005934cellular_componentcellular bud tip
F0005935cellular_componentcellular bud neck
F0006075biological_process(1->3)-beta-D-glucan biosynthetic process
F0007015biological_processactin filament organization
F0007117biological_processbudding cell bud growth
F0007165biological_processsignal transduction
F0007264biological_processsmall GTPase-mediated signal transduction
F0008047molecular_functionenzyme activator activity
F0008361biological_processregulation of cell size
F0009272biological_processfungal-type cell wall biogenesis
F0009277cellular_componentfungal-type cell wall
F0010008cellular_componentendosome membrane
F0016020cellular_componentmembrane
F0016787molecular_functionhydrolase activity
F0019901molecular_functionprotein kinase binding
F0030036biological_processactin cytoskeleton organization
F0030476biological_processascospore wall assembly
F0031160cellular_componentspore wall
F0031681molecular_functionG-protein beta-subunit binding
F0032186biological_processcellular bud neck septin ring organization
F0032880biological_processregulation of protein localization
F0032889biological_processregulation of vacuole fusion, non-autophagic
F0032956biological_processregulation of actin cytoskeleton organization
F0043332cellular_componentmating projection tip
F0045807biological_processpositive regulation of endocytosis
F0060178biological_processregulation of exocyst localization
F0060237biological_processregulation of fungal-type cell wall organization
F0071944cellular_componentcell periphery
F0090037biological_processpositive regulation of protein kinase C signaling
F0090334biological_processregulation of cell wall (1->3)-beta-D-glucan biosynthetic process
F1903395biological_processregulation of secondary cell septum biogenesis
F1903501biological_processpositive regulation of mitotic actomyosin contractile ring assembly
Functional Information from PDB Data
site_idAC1
Number of Residues3
DetailsBINDING SITE FOR RESIDUE PO4 A 321
ChainResidue
AARG168
ALYS194
ATYR196

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE PO4 A 322
ChainResidue
ALYS135
AARG137
ALYS155
AHOH347

site_idAC3
Number of Residues4
DetailsBINDING SITE FOR RESIDUE PO4 A 323
ChainResidue
AARG157
AHOH333
ALYS135
AARG137

site_idAC4
Number of Residues25
DetailsBINDING SITE FOR RESIDUE GNP B 301
ChainResidue
BASP18
BGLY19
BALA20
BCYS21
BGLY22
BLYS23
BTHR24
BCYS25
BPHE35
BPRO36
BGLU37
BTYR39
BPRO41
BTHR42
BTHR65
BGLY67
BLYS123
BASP125
BSER165
BALA166
BLYS167
BHOH189
BHOH194
BHOH195
BMG401

site_idAC5
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MG B 401
ChainResidue
BTHR24
BTHR42
BHOH194
BHOH195
BGNP301

site_idAC6
Number of Residues3
DetailsBINDING SITE FOR RESIDUE PO4 C 321
ChainResidue
CARG168
CLYS194
CTYR196

site_idAC7
Number of Residues4
DetailsBINDING SITE FOR RESIDUE PO4 C 322
ChainResidue
CLYS135
CARG137
CLYS155
CHOH338

site_idAC8
Number of Residues3
DetailsBINDING SITE FOR RESIDUE PO4 C 323
ChainResidue
CARG137
CARG157
CHOH326

site_idAC9
Number of Residues24
DetailsBINDING SITE FOR RESIDUE GNP D 301
ChainResidue
DASP18
DGLY19
DALA20
DCYS21
DGLY22
DLYS23
DTHR24
DCYS25
DPHE35
DPRO36
DGLU37
DTYR39
DPRO41
DTHR42
DGLY67
DLYS123
DASP125
DSER165
DALA166
DLYS167
DHOH189
DHOH194
DHOH213
DMG401

site_idBC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MG D 401
ChainResidue
DTHR24
DTHR42
DHOH189
DHOH213
DGNP301

site_idBC2
Number of Residues3
DetailsBINDING SITE FOR RESIDUE PO4 E 321
ChainResidue
ELYS135
EARG137
EARG157

site_idBC3
Number of Residues23
DetailsBINDING SITE FOR RESIDUE GNP F 301
ChainResidue
FLEU126
FSER165
FALA166
FLYS167
FHOH189
FHOH195
FMG401
CGLN219
FGLY19
FALA20
FCYS21
FGLY22
FLYS23
FTHR24
FCYS25
FPHE35
FPRO36
FGLU37
FTYR39
FTHR42
FGLY67
FLYS123
FASP125

site_idBC4
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MG F 401
ChainResidue
FTHR24
FTHR42
FHOH189
FHOH195
FGNP301

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues6
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:P61586
ChainResidueDetails
BGLY17
BCYS122
DGLY17
DCYS122
FGLY17
FCYS122

site_idSWS_FT_FI2
Number of Residues3
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
BASP64
DASP64
FASP64

site_idSWS_FT_FI3
Number of Residues3
DetailsMOD_RES: N-acetylserine => ECO:0000269|Ref.5, ECO:0007744|PubMed:22814378
ChainResidueDetails
BSER2
DSER2
FSER2

221051

PDB entries from 2024-06-12

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