3A46

Crystal structure of MvNei1/THF complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0003677	molecular_function	DNA binding
A	0003684	molecular_function	damaged DNA binding
A	0003906	molecular_function	DNA-(apurinic or apyrimidinic site) endonuclease activity
A	0006281	biological_process	DNA repair
A	0006284	biological_process	base-excision repair
A	0008270	molecular_function	zinc ion binding
A	0008534	molecular_function	oxidized purine nucleobase lesion DNA N-glycosylase activity
A	0016787	molecular_function	hydrolase activity
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0016799	molecular_function	hydrolase activity, hydrolyzing N-glycosyl compounds
A	0016829	molecular_function	lyase activity
A	0019104	molecular_function	DNA N-glycosylase activity
A	0034039	molecular_function	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity
A	0140078	molecular_function	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B	0003676	molecular_function	nucleic acid binding
B	0003677	molecular_function	DNA binding
B	0003684	molecular_function	damaged DNA binding
B	0003906	molecular_function	DNA-(apurinic or apyrimidinic site) endonuclease activity
B	0006281	biological_process	DNA repair
B	0006284	biological_process	base-excision repair
B	0008270	molecular_function	zinc ion binding
B	0008534	molecular_function	oxidized purine nucleobase lesion DNA N-glycosylase activity
B	0016787	molecular_function	hydrolase activity
B	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
B	0016799	molecular_function	hydrolase activity, hydrolyzing N-glycosyl compounds
B	0016829	molecular_function	lyase activity
B	0019104	molecular_function	DNA N-glycosylase activity
B	0034039	molecular_function	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity
B	0140078	molecular_function	class I DNA-(apurinic or apyrimidinic site) endonuclease activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 3545

Chain	Residue
A	LYS274
A	ARG277
A	HOH2017
C	DC6
D	DG21
D	HOH2070

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Schiff-base intermediate with DNA => ECO:0000255|PROSITE-ProRule:PRU00392

Chain	Residue	Details
A	PRO2
B	PRO2

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site_id	SWS_FT_FI2
Number of Residues	2
Details	ACT_SITE: Proton donor => ECO:0000255|PROSITE-ProRule:PRU00392

Chain	Residue	Details
A	GLU3
B	GLU3

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site_id	SWS_FT_FI3
Number of Residues	2
Details	ACT_SITE: Proton donor; for beta-elimination activity => ECO:0000255|PROSITE-ProRule:PRU00392

Chain	Residue	Details
A	LYS58
B	LYS58

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site_id	SWS_FT_FI4
Number of Residues	2
Details	ACT_SITE: Proton donor; for delta-elimination activity => ECO:0000255|PROSITE-ProRule:PRU00392

Chain	Residue	Details
A	ARG277
B	ARG277

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	Annotated By Reference To The Literature 1k82

Chain	Residue	Details
A	PRO2
A	LYS60
A	ARG277
A	GLU3

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site_id	CSA2
Number of Residues	4
Details	Annotated By Reference To The Literature 1k82

Chain	Residue	Details
B	PRO2
B	LYS60
B	ARG277
B	GLU3

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