Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0031012 | cellular_component | extracellular matrix |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 1265 |
| Chain | Residue |
| A | ASP175 |
| A | GLY176 |
| A | GLY178 |
| A | THR180 |
| A | ASP198 |
| A | GLU201 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 1266 |
| Chain | Residue |
| A | ASP194 |
| A | HOH2043 |
| A | HOH2061 |
| A | ASP158 |
| A | GLY190 |
| A | GLY192 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 1267 |
| Chain | Residue |
| A | HIS168 |
| A | ASP170 |
| A | HIS183 |
| A | HIS196 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 1268 |
| Chain | Residue |
| A | HIS219 |
| A | HIS223 |
| A | HIS229 |
| A | TQJ1271 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1269 |
| Chain | Residue |
| A | PRO126 |
| A | HIS127 |
| A | ILE128 |
| A | ASN234 |
| A | HOH2100 |
| A | HOH2101 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1270 |
| Chain | Residue |
| A | ASN234 |
| A | SER252 |
| A | GLN253 |
| A | HOH2087 |
| A | HOH2101 |
| A | HOH2102 |
| site_id | AC7 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE TQJ A 1271 |
| Chain | Residue |
| A | TYR172 |
| A | LEU181 |
| A | ALA182 |
| A | HIS183 |
| A | TYR215 |
| A | HIS219 |
| A | GLU220 |
| A | HIS223 |
| A | HIS229 |
| A | VAL236 |
| A | TYR238 |
| A | PRO239 |
| A | THR240 |
| A | TYR241 |
| A | ZN1268 |
| A | HOH2057 |
| A | HOH2103 |
| A | HOH2104 |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. AATHELGHSL |
| Chain | Residue | Details |
| A | ALA216-LEU225 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: |
| Chain | Residue | Details |
| A | GLU220 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 17 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | ASP158 | |
| A | ASP170 | |
| A | ASP175 | |
| A | GLY176 | |
| A | GLY178 | |
| A | THR180 | |
| A | HIS183 | |
| A | GLY190 | |
| A | GLY192 | |
| A | ASP194 | |
| A | HIS196 | |
| A | ASP198 | |
| A | GLU201 | |
| A | HIS219 | |
| A | HIS223 | |
| A | HIS229 | |
| A | HIS168 | |
