Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

2X86

AGME bound to ADP-B-mannose

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005975	biological_process	carbohydrate metabolic process
A	0008712	molecular_function	ADP-glyceromanno-heptose 6-epimerase activity
A	0009244	biological_process	lipopolysaccharide core region biosynthetic process
A	0016853	molecular_function	isomerase activity
A	0050661	molecular_function	NADP binding
A	0097171	biological_process	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
B	0005975	biological_process	carbohydrate metabolic process
B	0008712	molecular_function	ADP-glyceromanno-heptose 6-epimerase activity
B	0009244	biological_process	lipopolysaccharide core region biosynthetic process
B	0016853	molecular_function	isomerase activity
B	0050661	molecular_function	NADP binding
B	0097171	biological_process	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C	0005975	biological_process	carbohydrate metabolic process
C	0008712	molecular_function	ADP-glyceromanno-heptose 6-epimerase activity
C	0009244	biological_process	lipopolysaccharide core region biosynthetic process
C	0016853	molecular_function	isomerase activity
C	0050661	molecular_function	NADP binding
C	0097171	biological_process	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D	0005975	biological_process	carbohydrate metabolic process
D	0008712	molecular_function	ADP-glyceromanno-heptose 6-epimerase activity
D	0009244	biological_process	lipopolysaccharide core region biosynthetic process
D	0016853	molecular_function	isomerase activity
D	0050661	molecular_function	NADP binding
D	0097171	biological_process	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
E	0005975	biological_process	carbohydrate metabolic process
E	0008712	molecular_function	ADP-glyceromanno-heptose 6-epimerase activity
E	0009244	biological_process	lipopolysaccharide core region biosynthetic process
E	0016853	molecular_function	isomerase activity
E	0050661	molecular_function	NADP binding
E	0097171	biological_process	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
F	0005975	biological_process	carbohydrate metabolic process
F	0008712	molecular_function	ADP-glyceromanno-heptose 6-epimerase activity
F	0009244	biological_process	lipopolysaccharide core region biosynthetic process
F	0016853	molecular_function	isomerase activity
F	0050661	molecular_function	NADP binding
F	0097171	biological_process	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
G	0005975	biological_process	carbohydrate metabolic process
G	0008712	molecular_function	ADP-glyceromanno-heptose 6-epimerase activity
G	0009244	biological_process	lipopolysaccharide core region biosynthetic process
G	0016853	molecular_function	isomerase activity
G	0050661	molecular_function	NADP binding
G	0097171	biological_process	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
H	0005975	biological_process	carbohydrate metabolic process
H	0008712	molecular_function	ADP-glyceromanno-heptose 6-epimerase activity
H	0009244	biological_process	lipopolysaccharide core region biosynthetic process
H	0016853	molecular_function	isomerase activity
H	0050661	molecular_function	NADP binding
H	0097171	biological_process	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
I	0005975	biological_process	carbohydrate metabolic process
I	0008712	molecular_function	ADP-glyceromanno-heptose 6-epimerase activity
I	0009244	biological_process	lipopolysaccharide core region biosynthetic process
I	0016853	molecular_function	isomerase activity
I	0050661	molecular_function	NADP binding
I	0097171	biological_process	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J	0005975	biological_process	carbohydrate metabolic process
J	0008712	molecular_function	ADP-glyceromanno-heptose 6-epimerase activity
J	0009244	biological_process	lipopolysaccharide core region biosynthetic process
J	0016853	molecular_function	isomerase activity
J	0050661	molecular_function	NADP binding
J	0097171	biological_process	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
K	0005975	biological_process	carbohydrate metabolic process
K	0008712	molecular_function	ADP-glyceromanno-heptose 6-epimerase activity
K	0009244	biological_process	lipopolysaccharide core region biosynthetic process
K	0016853	molecular_function	isomerase activity
K	0050661	molecular_function	NADP binding
K	0097171	biological_process	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
L	0005975	biological_process	carbohydrate metabolic process
L	0008712	molecular_function	ADP-glyceromanno-heptose 6-epimerase activity
L	0009244	biological_process	lipopolysaccharide core region biosynthetic process
L	0016853	molecular_function	isomerase activity
L	0050661	molecular_function	NADP binding
L	0097171	biological_process	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
M	0005975	biological_process	carbohydrate metabolic process
M	0008712	molecular_function	ADP-glyceromanno-heptose 6-epimerase activity
M	0009244	biological_process	lipopolysaccharide core region biosynthetic process
M	0016853	molecular_function	isomerase activity
M	0050661	molecular_function	NADP binding
M	0097171	biological_process	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
N	0005975	biological_process	carbohydrate metabolic process
N	0008712	molecular_function	ADP-glyceromanno-heptose 6-epimerase activity
N	0009244	biological_process	lipopolysaccharide core region biosynthetic process
N	0016853	molecular_function	isomerase activity
N	0050661	molecular_function	NADP binding
N	0097171	biological_process	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
O	0005975	biological_process	carbohydrate metabolic process
O	0008712	molecular_function	ADP-glyceromanno-heptose 6-epimerase activity
O	0009244	biological_process	lipopolysaccharide core region biosynthetic process
O	0016853	molecular_function	isomerase activity
O	0050661	molecular_function	NADP binding
O	0097171	biological_process	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
P	0005975	biological_process	carbohydrate metabolic process
P	0008712	molecular_function	ADP-glyceromanno-heptose 6-epimerase activity
P	0009244	biological_process	lipopolysaccharide core region biosynthetic process
P	0016853	molecular_function	isomerase activity
P	0050661	molecular_function	NADP binding
P	0097171	biological_process	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Q	0005975	biological_process	carbohydrate metabolic process
Q	0008712	molecular_function	ADP-glyceromanno-heptose 6-epimerase activity
Q	0009244	biological_process	lipopolysaccharide core region biosynthetic process
Q	0016853	molecular_function	isomerase activity
Q	0050661	molecular_function	NADP binding
Q	0097171	biological_process	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
R	0005975	biological_process	carbohydrate metabolic process
R	0008712	molecular_function	ADP-glyceromanno-heptose 6-epimerase activity
R	0009244	biological_process	lipopolysaccharide core region biosynthetic process
R	0016853	molecular_function	isomerase activity
R	0050661	molecular_function	NADP binding
R	0097171	biological_process	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
S	0005975	biological_process	carbohydrate metabolic process
S	0008712	molecular_function	ADP-glyceromanno-heptose 6-epimerase activity
S	0009244	biological_process	lipopolysaccharide core region biosynthetic process
S	0016853	molecular_function	isomerase activity
S	0050661	molecular_function	NADP binding
S	0097171	biological_process	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
T	0005975	biological_process	carbohydrate metabolic process
T	0008712	molecular_function	ADP-glyceromanno-heptose 6-epimerase activity
T	0009244	biological_process	lipopolysaccharide core region biosynthetic process
T	0016853	molecular_function	isomerase activity
T	0050661	molecular_function	NADP binding
T	0097171	biological_process	ADP-L-glycero-beta-D-manno-heptose biosynthetic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	40
Details	ACT_SITE: Proton acceptor => ECO:0000255\|HAMAP-Rule:MF_01601

Chain	Residue	Details
A	PHE140
A	LYS178
B	PHE140
B	LYS178
C	PHE140
C	LYS178
D	PHE140
D	LYS178
E	PHE140
E	LYS178
F	PHE140
F	LYS178
G	PHE140
G	LYS178
H	PHE140
H	LYS178
I	PHE140
I	LYS178
J	PHE140
J	LYS178
K	PHE140
K	LYS178
L	PHE140
L	LYS178
M	PHE140
M	LYS178
N	PHE140
N	LYS178
O	PHE140
O	LYS178
P	PHE140
P	LYS178
Q	PHE140
Q	LYS178
R	PHE140
R	LYS178
S	PHE140
S	LYS178
T	PHE140
T	LYS178

site_id	SWS_FT_FI2
Number of Residues	300
Details	BINDING: BINDING => ECO:0000255\|HAMAP-Rule:MF_01601

Chain	Residue	Details
C	SER180
C	HIS187
C	PHE201
C	ARG209
C	TYR272
D	PHE10
D	ASP31
D	LYS38
D	LYS53
D	GLU75
D	ASN92
D	LYS144
D	ASN169
D	VAL170
D	LYS178
D	SER180
D	HIS187
D	PHE201
D	ARG209
D	TYR272
E	PHE10
E	ASP31
E	LYS38
E	LYS53
E	GLU75
E	ASN92
E	LYS144
E	ASN169
E	VAL170
E	LYS178
E	SER180
E	HIS187
E	PHE201
E	ARG209
E	TYR272
F	PHE10
F	ASP31
F	LYS38
F	LYS53
F	GLU75
F	ASN92
F	LYS144
F	ASN169
F	VAL170
F	LYS178
F	SER180
F	HIS187
F	PHE201
F	ARG209
F	TYR272
G	PHE10
G	ASP31
G	LYS38
G	LYS53
G	GLU75
G	ASN92
G	LYS144
G	ASN169
G	VAL170
G	LYS178
G	SER180
G	HIS187
G	PHE201
G	ARG209
G	TYR272
H	PHE10
H	ASP31
H	LYS38
H	LYS53
H	GLU75
H	ASN92
H	LYS144
H	ASN169
H	VAL170
H	LYS178
H	SER180
H	HIS187
H	PHE201
H	ARG209
H	TYR272
I	PHE10
I	ASP31
I	LYS38
I	LYS53
I	GLU75
I	ASN92
I	LYS144
I	ASN169
I	VAL170
I	LYS178
I	SER180
I	HIS187
I	PHE201
I	ARG209
I	TYR272
J	PHE10
J	ASP31
J	LYS38
J	LYS53
J	GLU75
J	ASN92
J	LYS144
J	ASN169
J	VAL170
J	LYS178
J	SER180
J	HIS187
J	PHE201
J	ARG209
J	TYR272
K	PHE10
K	ASP31
K	LYS38
K	LYS53
K	GLU75
K	ASN92
K	LYS144
K	ASN169
K	VAL170
K	LYS178
K	SER180
K	HIS187
K	PHE201
K	ARG209
K	TYR272
L	PHE10
L	ASP31
L	LYS38
L	LYS53
L	GLU75
L	ASN92
L	LYS144
L	ASN169
L	VAL170
L	LYS178
L	SER180
L	HIS187
L	PHE201
L	ARG209
L	TYR272
M	PHE10
M	ASP31
M	LYS38
M	LYS53
M	GLU75
M	ASN92
M	LYS144
M	ASN169
M	VAL170
M	LYS178
M	SER180
M	HIS187
M	PHE201
M	ARG209
M	TYR272
N	PHE10
N	ASP31
N	LYS38
N	LYS53
N	GLU75
N	ASN92
N	LYS144
N	ASN169
N	VAL170
N	LYS178
N	SER180
N	HIS187
N	PHE201
N	ARG209
N	TYR272
O	PHE10
O	ASP31
O	LYS38
O	LYS53
O	GLU75
O	ASN92
O	LYS144
O	ASN169
O	VAL170
O	LYS178
O	SER180
O	HIS187
O	PHE201
O	ARG209
O	TYR272
P	PHE10
P	ASP31
P	LYS38
P	LYS53
P	GLU75
P	ASN92
P	LYS144
P	ASN169
P	VAL170
P	LYS178
P	SER180
P	HIS187
P	PHE201
P	ARG209
P	TYR272
Q	PHE10
Q	ASP31
Q	LYS38
Q	LYS53
Q	GLU75
Q	ASN92
Q	LYS144
Q	ASN169
Q	VAL170
Q	LYS178
Q	SER180
Q	HIS187
Q	PHE201
Q	ARG209
Q	TYR272
R	PHE10
R	ASP31
R	LYS38
R	LYS53
R	GLU75
R	ASN92
R	LYS144
R	ASN169
R	VAL170
R	LYS178
R	SER180
R	HIS187
R	PHE201
R	ARG209
R	TYR272
S	PHE10
S	ASP31
S	LYS38
S	LYS53
S	GLU75
S	ASN92
S	LYS144
S	ASN169
S	VAL170
S	LYS178
S	SER180
S	HIS187
S	PHE201
S	ARG209
S	TYR272
T	PHE10
T	ASP31
T	LYS38
T	LYS53
T	GLU75
T	ASN92
T	LYS144
T	ASN169
T	VAL170
T	LYS178
T	SER180
T	HIS187
T	PHE201
T	ARG209
T	TYR272
A	PHE10
A	ASP31
A	LYS38
A	LYS53
A	GLU75
A	ASN92
A	LYS144
A	ASN169
A	VAL170
A	LYS178
A	SER180
A	HIS187
A	PHE201
A	ARG209
A	TYR272
B	PHE10
B	ASP31
B	LYS38
B	LYS53
B	GLU75
B	ASN92
B	LYS144
B	ASN169
B	VAL170
B	LYS178
B	SER180
B	HIS187
B	PHE201
B	ARG209
B	TYR272
C	PHE10
C	ASP31
C	LYS38
C	LYS53
C	GLU75
C	ASN92
C	LYS144
C	ASN169
C	VAL170
C	LYS178

site_id	SWS_FT_FI3
Number of Residues	20
Details	MOD_RES: N6-acetyllysine => ECO:0000255\|HAMAP-Rule:MF_01601

Chain	Residue	Details
A	LYS267
B	LYS267
C	LYS267
D	LYS267
E	LYS267
F	LYS267
G	LYS267
H	LYS267
I	LYS267
J	LYS267
K	LYS267
L	LYS267
M	LYS267
N	LYS267
O	LYS267
P	LYS267
Q	LYS267
R	LYS267
S	LYS267
T	LYS267

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)