2WYI
Structure of the Streptococcus pyogenes family GH38 alpha-mannosidase complexed with swainsonine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004559 | molecular_function | alpha-mannosidase activity |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0006013 | biological_process | mannose metabolic process |
| A | 0009313 | biological_process | oligosaccharide catabolic process |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0030246 | molecular_function | carbohydrate binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004559 | molecular_function | alpha-mannosidase activity |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0006013 | biological_process | mannose metabolic process |
| B | 0009313 | biological_process | oligosaccharide catabolic process |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0030246 | molecular_function | carbohydrate binding |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PG0 A 1902 |
| Chain | Residue |
| A | TYR303 |
| A | GLU771 |
| A | LEU775 |
| A | LYS777 |
| A | PG01903 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PG0 A 1903 |
| Chain | Residue |
| A | GLU771 |
| A | PG01902 |
| A | HOH2218 |
| B | PG01902 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE PG0 A 1904 |
| Chain | Residue |
| A | GLY802 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PG0 A 1905 |
| Chain | Residue |
| A | ARG310 |
| A | TYR374 |
| A | HOH2221 |
| A | HOH2222 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 1906 |
| Chain | Residue |
| A | HIS13 |
| A | ASP15 |
| A | ASP125 |
| A | HIS351 |
| A | SWA1907 |
| site_id | AC6 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE SWA A 1907 |
| Chain | Residue |
| A | HIS13 |
| A | ASP15 |
| A | TRP18 |
| A | ASP125 |
| A | PHE127 |
| A | ARG149 |
| A | TYR192 |
| A | ASP232 |
| A | HIS351 |
| A | ASP352 |
| A | TYR574 |
| A | ASP763 |
| A | ZN1906 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PG0 B 1902 |
| Chain | Residue |
| A | PG01903 |
| B | LEU775 |
| B | HOH2114 |
| B | HOH2116 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PG0 B 1903 |
| Chain | Residue |
| B | ARG310 |
| B | TYR374 |
| B | PG01905 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PG0 B 1904 |
| Chain | Residue |
| B | GLY802 |
| B | PG01905 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PG0 B 1905 |
| Chain | Residue |
| B | ARG310 |
| B | SER781 |
| B | PG01903 |
| B | PG01904 |
| B | HOH2123 |
| site_id | BC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE PG0 B 1906 |
| Chain | Residue |
| B | ALA624 |
| site_id | BC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE PG0 B 1907 |
| Chain | Residue |
| B | ARG149 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 1908 |
| Chain | Residue |
| B | HIS13 |
| B | ASP15 |
| B | ASP125 |
| B | HIS351 |
| B | SWA1909 |
| site_id | BC5 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE SWA B 1909 |
| Chain | Residue |
| B | HIS13 |
| B | ASP15 |
| B | TRP18 |
| B | ASP125 |
| B | PHE127 |
| B | ARG149 |
| B | TYR192 |
| B | ASP232 |
| B | HIS351 |
| B | ASP352 |
| B | TYR574 |
| B | ASP763 |
| B | ZN1908 |
