Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

2V9P

Crystal structure of papillomavirus E1 hexameric helicase DNA-free form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003678	molecular_function	DNA helicase activity
A	0005524	molecular_function	ATP binding
A	0006260	biological_process	DNA replication
B	0003677	molecular_function	DNA binding
B	0003678	molecular_function	DNA helicase activity
B	0005524	molecular_function	ATP binding
B	0006260	biological_process	DNA replication
C	0003677	molecular_function	DNA binding
C	0003678	molecular_function	DNA helicase activity
C	0005524	molecular_function	ATP binding
C	0006260	biological_process	DNA replication
D	0003677	molecular_function	DNA binding
D	0003678	molecular_function	DNA helicase activity
D	0005524	molecular_function	ATP binding
D	0006260	biological_process	DNA replication
E	0003677	molecular_function	DNA binding
E	0003678	molecular_function	DNA helicase activity
E	0005524	molecular_function	ATP binding
E	0006260	biological_process	DNA replication
F	0003677	molecular_function	DNA binding
F	0003678	molecular_function	DNA helicase activity
F	0005524	molecular_function	ATP binding
F	0006260	biological_process	DNA replication
G	0003677	molecular_function	DNA binding
G	0003678	molecular_function	DNA helicase activity
G	0005524	molecular_function	ATP binding
G	0006260	biological_process	DNA replication
H	0003677	molecular_function	DNA binding
H	0003678	molecular_function	DNA helicase activity
H	0005524	molecular_function	ATP binding
H	0006260	biological_process	DNA replication
I	0003677	molecular_function	DNA binding
I	0003678	molecular_function	DNA helicase activity
I	0005524	molecular_function	ATP binding
I	0006260	biological_process	DNA replication
J	0003677	molecular_function	DNA binding
J	0003678	molecular_function	DNA helicase activity
J	0005524	molecular_function	ATP binding
J	0006260	biological_process	DNA replication
K	0003677	molecular_function	DNA binding
K	0003678	molecular_function	DNA helicase activity
K	0005524	molecular_function	ATP binding
K	0006260	biological_process	DNA replication
L	0003677	molecular_function	DNA binding
L	0003678	molecular_function	DNA helicase activity
L	0005524	molecular_function	ATP binding
L	0006260	biological_process	DNA replication

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PO4 A1580

Chain	Residue
A	ASN436
A	THR437
A	GLY438
A	LYS439
A	SER440
A	PO41581
A	MG1582

site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 A1581

Chain	Residue
A	LYS439
A	ASP479
A	ASN523
A	PO41580
A	MG1582
B	ARG538
A	PRO435
A	ASN436

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A1582

Chain	Residue
A	SER440
A	ASP479
A	PO41580
A	PO41581
B	ARG538

site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 B1579

Chain	Residue
B	ASN436
B	THR437
B	GLY438
B	LYS439
B	SER440
B	MET441
B	PO41580
B	MG1581

site_id	AC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 B1580

Chain	Residue
B	PRO435
B	ASN436
B	LYS439
B	ASP479
B	ASN523
B	PO41579
B	MG1581
C	ARG538

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG B1581

Chain	Residue
B	SER440
B	ASP479
B	PO41579
B	PO41580
C	ARG538

site_id	AC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 C1579

Chain	Residue
C	ASN436
C	THR437
C	GLY438
C	LYS439
C	SER440
C	MET441
C	PO41580
C	MG1581

site_id	AC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 C1580

Chain	Residue
C	PRO435
C	ASN436
C	LYS439
C	ASP479
C	ASN523
C	PO41579
C	MG1581
D	ARG538

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG C1581

Chain	Residue
C	SER440
C	ASP479
C	PO41579
C	PO41580

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PO4 D1580

Chain	Residue
D	ASN436
D	THR437
D	GLY438
D	LYS439
D	SER440

site_id	BC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PO4 E1579

Chain	Residue
E	ASN436
E	THR437
E	GLY438
E	LYS439
E	SER440
F	TYR534

site_id	BC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PO4 F1580

Chain	Residue
F	ASN436
F	THR437
F	GLY438
F	LYS439
F	SER440

site_id	BC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PO4 G1579

Chain	Residue
G	ASN436
G	THR437
G	GLY438
G	LYS439
G	SER440
G	PO41580
G	MG1581

site_id	BC5
Number of Residues	9
Details	BINDING SITE FOR RESIDUE PO4 G1580

Chain	Residue
G	PRO435
G	ASN436
G	LYS439
G	ASP479
G	ASN523
G	PO41579
G	MG1581
H	TYR534
H	ARG538

site_id	BC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG G1581

Chain	Residue
G	SER440
G	ASP479
G	PO41579
G	PO41580
H	ARG538

site_id	BC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 H1579

Chain	Residue
H	THR437
H	GLY438
H	LYS439
H	SER440
H	MET441
H	PO41580
H	MG1581
H	ASN436

site_id	BC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 H1580

Chain	Residue
H	PRO435
H	ASN436
H	LYS439
H	ASP479
H	ASN523
H	PO41579
H	MG1581
I	ARG538

site_id	BC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG H1581

Chain	Residue
H	SER440
H	ASP479
H	PO41579
H	PO41580

site_id	CC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 I1580

Chain	Residue
I	ASN436
I	THR437
I	GLY438
I	LYS439
I	SER440
I	MET441
I	PO41581
I	MG1582

site_id	CC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 I1581

Chain	Residue
I	PRO435
I	ASN436
I	LYS439
I	ASP479
I	ASN523
I	PO41580
I	MG1582
J	ARG538

site_id	CC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG I1582

Chain	Residue
I	SER440
I	ASP479
I	PO41580
I	PO41581

site_id	CC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PO4 J1578

Chain	Residue
J	ASN436
J	THR437
J	GLY438
J	LYS439
J	SER440
K	TYR534

site_id	CC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PO4 K1580

Chain	Residue
K	ASN436
K	THR437
K	GLY438
K	LYS439
K	SER440
L	TYR534

site_id	CC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PO4 L1579

Chain	Residue
L	ASN436
L	THR437
L	GLY438
L	LYS439
L	SER440

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	BINDING: BINDING => ECO:0000255\|HAMAP-Rule:MF_04000

Chain	Residue	Details
A	GLY433
B	GLY433
C	GLY433
D	GLY433
E	GLY433
F	GLY433
G	GLY433
H	GLY433
I	GLY433
J	GLY433
K	GLY433
L	GLY433

site_id	SWS_FT_FI2
Number of Residues	24
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) => ECO:0000255\|HAMAP-Rule:MF_04000, ECO:0000269\|PubMed:11005821

Chain	Residue	Details
A	LYS514
B	LYS514
C	LYS514
D	LYS514
E	LYS514
F	LYS514
G	LYS514
H	LYS514
I	LYS514
J	LYS514
K	LYS514
L	LYS514

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)