2V85
Crystal structure of RAG2-PHD finger in complex with H3R2me1K4me3 peptide
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 1488 |
| Chain | Residue |
| A | CYS419 |
| A | CYS423 |
| A | HIS455 |
| A | CYS458 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 1489 |
| Chain | Residue |
| A | CYS446 |
| A | HIS452 |
| A | CYS478 |
| A | HIS481 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 1487 |
| Chain | Residue |
| B | CYS423 |
| B | HIS455 |
| B | CYS458 |
| B | CYS419 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 1488 |
| Chain | Residue |
| B | CYS446 |
| B | HIS452 |
| B | CYS478 |
| B | HIS481 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | MOD_RES: Citrulline; alternate => ECO:0000269|PubMed:16567635 |
| Chain | Residue | Details |
| D | NMM2 | |
| E | NMM2 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine; by HASPIN => ECO:0000269|PubMed:15681610, ECO:0000269|PubMed:16185088 |
| Chain | Residue | Details |
| D | THR3 | |
| B | CYS423 | |
| B | CYS446 | |
| B | HIS452 | |
| B | HIS455 | |
| B | CYS458 | |
| B | CYS478 | |
| B | HIS481 | |
| E | THR3 | |
| A | CYS446 | |
| A | HIS452 | |
| A | HIS455 | |
| A | CYS458 | |
| A | CYS478 | |
| A | HIS481 | |
| B | CYS419 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:16267050, ECO:0000269|PubMed:16457588, ECO:0000269|PubMed:17194708 |
| Chain | Residue | Details |
| D | M3L4 | |
| E | M3L4 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: 5-glutamyl serotonin; alternate => ECO:0000269|PubMed:30867594 |
| Chain | Residue | Details |
| D | GLN5 | |
| E | GLN5 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine; by PKC => ECO:0000269|PubMed:20228790 |
| Chain | Residue | Details |
| D | THR6 | |
| E | THR6 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | MOD_RES: Symmetric dimethylarginine; by PRMT5; alternate => ECO:0000250|UniProtKB:P68433 |
| Chain | Residue | Details |
| D | ARG8 | |
| E | ARG8 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:11242053, ECO:0000269|PubMed:16185088, ECO:0000269|PubMed:16267050, ECO:0000269|PubMed:16457588, ECO:0000269|PubMed:17194708 |
| Chain | Residue | Details |
| D | LYS9 | |
| E | LYS9 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; alternate; by AURKB, AURKC, RPS6KA3, RPS6KA4 and RPS6KA5 => ECO:0000269|PubMed:10464286, ECO:0000269|PubMed:11856369, ECO:0000269|PubMed:12560483, ECO:0000269|PubMed:15681610, ECO:0000269|PubMed:16185088, ECO:0000269|PubMed:16457588 |
| Chain | Residue | Details |
| D | ALA10 | |
| E | ALA10 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine; by PKC and CHEK1 => ECO:0000269|PubMed:12560483, ECO:0000269|PubMed:18066052, ECO:0000269|PubMed:18243098, ECO:0000269|PubMed:22901803 |
| Chain | Residue | Details |
| D | ALA11 | |
| E | ALA11 |
