2V82

KDPGal complexed to KDPGal

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008674	molecular_function	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity
A	0016829	molecular_function	lyase activity
A	0034194	biological_process	D-galactonate catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	15
Details	BINDING SITE FOR RESIDUE KDP A1207

Chain	Residue
A	ILE12
A	GLY155
A	GLY156
A	GLY176
A	SER177
A	HOH2047
A	HOH2061
A	ARG14
A	THR66
A	VAL85
A	THR86
A	PRO87
A	LYS126
A	PHE128
A	VAL154

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton donor/acceptor => ECO:0000305|PubMed:17981470

Chain	Residue	Details
A	GLU37

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: Schiff-base intermediate with substrate => ECO:0000269|PubMed:17981470

Chain	Residue	Details
A	LYS126

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:17981470

Chain	Residue	Details
A	ARG14
A	THR66

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	BINDING: covalent => ECO:0000269|PubMed:17981470

Chain	Residue	Details
A	LYS126

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	GLY156

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	BINDING:

Chain	Residue	Details
A	GLY176

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	SITE: Orients the nucleophilic substrate

Chain	Residue	Details
A	ARG14

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	SITE: Plays a major role in determining the stereoselectivity

Chain	Residue	Details
A	VAL154

---