2UYU

L-RHAMNULOSE-1-PHOSPHATE ALDOLASE FROM ESCHERICHIA COLI (MUTANT A88F- E192A)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005996	biological_process	monosaccharide metabolic process
A	0008994	molecular_function	rhamnulose-1-phosphate aldolase activity
A	0016829	molecular_function	lyase activity
A	0016830	molecular_function	carbon-carbon lyase activity
A	0016832	molecular_function	aldehyde-lyase activity
A	0019299	biological_process	rhamnose metabolic process
A	0019301	biological_process	rhamnose catabolic process
A	0019323	biological_process	pentose catabolic process
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0005996	biological_process	monosaccharide metabolic process
E	0008994	molecular_function	rhamnulose-1-phosphate aldolase activity
E	0016829	molecular_function	lyase activity
E	0016830	molecular_function	carbon-carbon lyase activity
E	0016832	molecular_function	aldehyde-lyase activity
E	0019299	biological_process	rhamnose metabolic process
E	0019301	biological_process	rhamnose catabolic process
E	0019323	biological_process	pentose catabolic process
E	0042802	molecular_function	identical protein binding
E	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A1275

Chain	Residue
A	HIS141
A	HIS143
A	GLU171
A	HIS212
A	HOH2167

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE A1276

Chain	Residue
E	GLU254
E	HOH2161
A	HIS204
A	HOH2123
A	HOH2125
A	HOH2126

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site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN E1275

Chain	Residue
E	HIS141
E	HIS143
E	GLU171
E	HIS212
E	HOH2174

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site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE E1276

Chain	Residue
E	HIS204
E	HOH2122
E	HOH2123
E	HOH2124

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: ACT_SITE => ECO:0000269|PubMed:11976494, ECO:0000269|PubMed:12962479

Chain	Residue	Details
A	GLU117
E	GLU117

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site_id	SWS_FT_FI2
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:11976494, ECO:0000269|PubMed:12962479

Chain	Residue	Details
A	HIS141
A	HIS143
A	HIS212
E	HIS141
E	HIS143
E	HIS212

---

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	5
Details	M-CSA 645

Chain	Residue	Details
A	GLU117	proton acceptor, proton donor
A	HIS141	metal ligand
A	HIS143	metal ligand
A	GLU171	proton donor
A	HIS212	metal ligand

---

site_id	MCSA2
Number of Residues	5
Details	M-CSA 645

Chain	Residue	Details
E	GLU117	proton acceptor, proton donor
E	HIS141	metal ligand
E	HIS143	metal ligand
E	GLU171	proton donor
E	HIS212	metal ligand

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