2REZ

Tetracenomycin ARO/CYC NaI Structure

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ACT A 155

Chain	Residue
A	ARG82
A	GLU84
A	GLY86
A	PRO87
A	PHE88
A	HOH287

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ACT A 156

Chain	Residue
A	ARG82
A	HOH286
A	GLU34
A	TRP63
A	TRP65

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site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 157

Chain	Residue
A	ARG82

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 159

Chain	Residue
A	ARG149
A	GLY151

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site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IOD A 161

Chain	Residue
A	ARG147
A	HOH162
A	HOH260

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor; for cyclase activity => ECO:0000305|PubMed:22432862

Chain	Residue	Details
A	SER67

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site_id	SWS_FT_FI2
Number of Residues	2
Details	ACT_SITE: Proton donor; for cyclase activity => ECO:0000305|PubMed:18388203, ECO:0000305|PubMed:22432862

Chain	Residue	Details
A	ARG69
A	ARG82

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